[HTML][HTML] Lactic acid bacteria—20 years exploring their potential as live vectors for mucosal vaccination

A Wyszyńska, P Kobierecka, J Bardowski… - Applied microbiology …, 2015 - Springer
Lactic acid bacteria (LAB) are a diverse group of Gram-positive, nonsporulating, low G+ C
content bacteria. Many of them have been given generally regarded as safe status. Over the …

[HTML][HTML] Innate and adaptive immune responses in the upper respiratory tract and the infectivity of SARS-CoV-2

R Ramasamy - Viruses, 2022 - mdpi.com
Increasing evidence shows the nasal epithelium to be the initial site of SARS-CoV-2
infection, and that early and effective immune responses in the upper respiratory tract (URT) …

[HTML][HTML] Needle-free, spirulina-produced Plasmodium falciparum circumsporozoite vaccination provides sterile protection against pre-erythrocytic malaria in mice

T Saveria, C Parthiban, AM Seilie, C Brady, A Martinez… - npj Vaccines, 2022 - nature.com
Antibodies against the Plasmodium falciparum circumsporozoite protein (PfCSP) can block
hepatocyte infection by sporozoites and protect against malaria. Needle-free vaccination …

Lactococcus lactis-based vaccines from laboratory bench to human use: an overview

M Bahey-El-Din - Vaccine, 2012 - Elsevier
Developing effective vaccines is an important weapon in the battle against potential
pathogens and their evolving antibiotic resistance trends. Several vaccine delivery vectors …

Oral Immunization with Recombinant Lactobacillus plantarum Induces a Protective Immune Response in Mice with Lyme Disease

B Del Rio, RJ Dattwyler, M Aroso, V Neves… - Clinical and Vaccine …, 2008 - Am Soc Microbiol
Mucosal immunization is advantageous over other routes of antigen delivery because it can
induce both mucosal and systemic immune responses. Our goal was to develop a mucosal …

[HTML][HTML] COVID-19 vaccines for optimizing immunity in the upper respiratory tract

R Ramasamy - Viruses, 2023 - mdpi.com
Rapid development and deployment of vaccines greatly reduced mortality and morbidity
during the COVID-19 pandemic. The most widely used COVID-19 vaccines approved by …

Use of lactobacilli and their pheromone-based regulatory mechanism in gene expression and drug delivery

DB Diep, G Mathiesen, VGH Eijsink… - Current pharmaceutical …, 2009 - ingentaconnect.com
Lactobacilli are common microorganisms in diverse vegetables and meat products and
several of these are also indigenous inhabitants in the gastro-intestinal (GI) tract of humans …

Surface display on lactic acid bacteria without genetic modification: strategies and applications

R Mao, D Wu, Y Wang - Applied microbiology and biotechnology, 2016 - Springer
Microbial cell surface display has attracted greater attention than ever and has numerous
potential applications in biotechnology. With the safety and probiotic properties, lactic acid …

Oral vaccine delivery: can it protect against non-mucosal pathogens?

L Wang, RL Coppel - Expert review of vaccines, 2008 - Taylor & Francis
Vaccination is an efficient and cost-effective form of preventing infectious diseases.
However, most currently available vaccines are delivered by injection, which makes mass …

[HTML][HTML] Intranasal immunization with recombinant Lactococci carrying human papillomavirus E7 protein and mouse interleukin‑12 DNA induces E7‑specific antitumor …

Y Li, X Li, H Liu, S Zhuang, J Yang… - Oncology …, 2014 - spandidos-publications.com
The use of Lactococcus lactis for the co‑delivery of antigens and cytokines has been shown
to successfully induce a special immune response. However, it is unknown whether the …