[HTML][HTML] Critical review of therapeutic potential of silymarin in cancer: A bioactive polyphenolic flavonoid

M Koushki, RF Yekta, N Amiri-Dashatan - Journal of Functional Foods, 2023 - Elsevier
Cancer is identified as second leading causes of death and imposes a significant
psychological and economic burden on societies. Due to its high prevalence, and a main …

[PDF][PDF] Milk thistle (Silybum marianum): a valuable medicinal plant with several therapeutic purposes

V Valková, H Ďúranová, J Bilčíková… - The Journal of …, 2020 - researchgate.net
Due to unmatched availability of chemical diversity, natural products from medicinal herbs
(as pure compounds or standardized extracts) provide unlimited opportunities for …

Silymarin induces inhibition of growth and apoptosis through modulation of the MAPK signaling pathway in AGS human gastric cancer cells

SH Kim, GS Choo, ES Yoo, JS Woo… - Oncology …, 2019 - spandidos-publications.com
Apoptosis is regarded as a therapeutic target because it is typically disturbed in human
cancer. Silymarin from milk thistle (Silybum marianum) has been reported to exhibit …

Formulation of silymarin-β cyclodextrin-TPGS inclusion complex: physicochemical characterization, molecular docking, and cell viability assessment against breast …

SS Imam, S Alshehri, MA Altamimi, WA Mahdi… - ACS …, 2023 - ACS Publications
Silymarin (SIL) is a poorly water-soluble flavonoid reported for different pharmacological
properties. Its therapeutic applications are limited due to poor water solubility. In this study …

Recapitulation of evidence of phytochemical, pharmacokinetic and biomedical application of silybin

A Islam, A Mishra, MA Siddiqui, S Siddiquie - Drug Research, 2021 - thieme-connect.com
Silymarin is a standardized extract obtained from seeds of Silybum marianum (SM)
belonging to the family Asteraceae. It is a flavonolignan complex and consists of various …

Silybum marianum: An overview of its phytochemistry and pharmacological activities with emphasis on potential anticancer properties

A Nawaz, S Zaib, I Khan, A Ahmed… - Anti-Cancer Agents …, 2023 - ingentaconnect.com
Silybum marianum (SM) belongs to the family Asteraceae, which holds therapeutic
significance in medicinal chemistry. Phytochemistry analysis revealed an abundance of …

Phytochemicals as the source of natural immunomodulator and their role in cancer chemoprevention

C Gupta, D Prakash - Immunomodulators and Human Health, 2022 - Springer
A well-functioning immune system of the host body plays critical role in the upkeep of regular
biological and immunological functions as well as inner milieu. Stable immunity augments …

[PDF][PDF] Ostropest plamisty (Silybum marianum [L.] Gaertn.)–fitochemia i efekty terapeutyczne

R Nurzyńska-Wierdak, J Dyduch, A Sawicka… - Annales …, 2018 - bibliotekanauki.pl
Ostropest plamisty (Silybum marianum (L.) Gaertn.) jest obecnie jednym z ważniejszych
gatunków roślin leczniczych uprawianym na plantacjach zielarskich. Surowcem zielarskim …

[PDF][PDF] Silymarin Effect on Mitophagy Pathway in the Human Colon Cancer HT-29 Cells

L Khorsandi, M Membini, G Saki… - Journal of Ilam …, 2023 - sjimu.medilam.ac.ir
اثر سیلیمارین بر مسیر میتوفاژی در سلول‌های سرطانی کولون انسانی HT-29 Page 1 © The
Author(s) Publisher: Ilam University of Medical Sciences Journal of Ilam University of Medical …

اثر سیلیمارین بر مسیر میتوفاژی در سلولهای سرطانی کولون انسانی HT-29-.

لعیاسادات خرسند&, مریم ممبینی… - Journal of Ilam …, 2022‎ - search.ebscohost.com
English Introduction: The anti-cancer effects of silymarin have been reported in several
studies. However, the mechanism of its action in colon cancer cells is not well understood …