Exosomes as a new frontier of cancer liquid biopsy

D Yu, Y Li, M Wang, J Gu, W Xu, H Cai, X Fang… - Molecular cancer, 2022 - Springer
Liquid biopsy, characterized by minimally invasive detection through biofluids such as
blood, saliva, and urine, has emerged as a revolutionary strategy for cancer diagnosis and …

Advances in surface plasmon resonance–based biosensor technologies for cancer biomarker detection

A Azzouz, L Hejji, KH Kim, D Kukkar, B Souhail… - Biosensors and …, 2022 - Elsevier
Surface plasmon resonance approach is a highly useful option to offer optical and label-free
detection of target bioanalytes with numerous advantages (eg, low-cost fabrication …

Facilitating in situ tumor imaging with a tetrahedral DNA framework‐enhanced hybridization chain reaction probe

B Zhang, T Tian, D Xiao, S Gao… - Advanced Functional …, 2022 - Wiley Online Library
Rapid and efficient tools for early cancer detection have diagnostic and therapeutic value.
Given that the DNA hairpin‐based hybridization chain reaction (HCR) is effective in …

Integrated SERS-vertical flow biosensor enabling multiplexed quantitative profiling of serological exosomal proteins in patients for accurate breast cancer subtyping

X Su, X Liu, Y Xie, M Chen, C Zheng, H Zhong, M Li - ACS nano, 2023 - ACS Publications
Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Exosome-mediated immunosuppression in tumor microenvironments

QH Xie, JQ Zheng, JY Ding, YF Wu, L Liu, ZL Yu… - Cells, 2022 - mdpi.com
Exosomes are membranous structures secreted by nearly all cell types. As critical
messengers for intercellular communication, exosomes deliver bioactive cargoes to …

Microfluidic‐based exosome analysis for liquid biopsy

B Lin, Y Lei, J Wang, L Zhu, Y Wu, H Zhang… - Small …, 2021 - Wiley Online Library
Liquid biopsy offers non‐invasive and real‐time molecular profiling of individual patients,
and is thus considered a revolutionary technology in precision medicine. Exosomes have …

Simultaneous detection of tumor derived exosomal protein–microRNA pairs with an Exo-PROS biosensor for cancer diagnosis

CC Hsu, Y Yang, E Kannisto, X Zeng, G Yu… - ACS …, 2023 - ACS Publications
Tumor derived exosomes (TEXs) have emerged as promising biomarkers for cancer liquid
biopsy. Conventional methods (such as ELISA and qRT-PCR) and emerging biosensing …

Personalized detection of circling exosomal PD-L1 based on Fe3O4@ TiO2 isolation and SERS immunoassay

Y Pang, J Shi, X Yang, C Wang, Z Sun… - Biosensors and …, 2020 - Elsevier
Circling exosomal PD-L1 can be expected as a predictor for the clinical responds of anti-PD-
1/PD-L1 therapy. Here, we present a simple method integrating capture and analysis of …

Optical, electrochemical and electrical (nano) biosensors for detection of exosomes: A comprehensive overview

L Xu, N Shoaie, F Jahanpeyma, J Zhao… - Biosensors and …, 2020 - Elsevier
Exosomes are small extracellular vesicles involved in many physiological activities of cells
in the human body. Exosomes from cancer cells have great potential to be applied in clinical …

[HTML][HTML] Current progress, strategy, and prospects of PD-1/PDL-1 immune checkpoint biosensing platforms for cancer diagnostics, therapy monitoring, and drug …

K Ratajczak, H Grel, P Olejnik, S Jakiela… - Biosensors and …, 2023 - Elsevier
Recent technological advancements in testing and monitoring instrumentation have greatly
contributed to the progress in cancer treatment by surgical, chemotherapeutic and …