Transition-metal-catalyzed C–H bond activation for the formation of C–C bonds in complex molecules

JH Docherty, TM Lister, G Mcarthur, MT Findlay… - Chemical …, 2023 - ACS Publications
Site-predictable and chemoselective C–H bond functionalization reactions offer synthetically
powerful strategies for the step-economic diversification of both feedstock and fine …

Ligand-promoted palladium-catalyzed aerobic oxidation reactions

D Wang, AB Weinstein, PB White, SS Stahl - Chemical reviews, 2017 - ACS Publications
Palladium-catalyzed aerobic oxidation reactions have been the focus of industrial
application and extensive research efforts for nearly 60 years. A significant transition …

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Z Lin, U Dhawa, X Hou, M Surke, B Yuan, SW Li… - Nature …, 2023 - nature.com
Electrooxidation has emerged as an increasingly viable platform in molecular syntheses that
can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical …

Organoelement chemistry: Promising growth areas and challenges

GA Abakumov, AV Piskunov… - Russian Chemical …, 2018 - iopscience.iop.org
The chemistry of organoelement compounds is now one of the most rapidly developing
fields of research, regarding both fundamental science and solution of applied problems …

Transition metal-catalyzed C–H functionalizations of indoles

P Kumar, PJ Nagtilak, M Kapur - New Journal of Chemistry, 2021 - pubs.rsc.org
Over the last two decades, transition-metal catalyzed C–H functionalization of indoles has
emerged as an area of extensive research and tremendous progress has been made in this …

Palladium/Norbornene‐Catalyzed Direct Vicinal Di‐Carbo‐Functionalization of Indoles: Reaction Development and Mechanistic Study

X Liu, Y Zhou, X Qi, R Li, P Liu… - Angewandte Chemie …, 2023 - Wiley Online Library
Methods that can simultaneously install multiple different functional groups to heteroarenes
via C− H functionalizations are valuable for complex molecule synthesis, which, however …

Oligothiophene Synthesis by a General C–H Activation Mechanism: Electrophilic Concerted Metalation–Deprotonation (eCMD)

L Wang, BP Carrow - ACS catalysis, 2019 - ACS Publications
Oxidative C–H/C–H coupling is a promising synthetic route for the streamlined construction
of conjugated organic materials for optoelectronic applications. Broader adoption of these …

Transition-Metal-Catalyzed Divergent C–H Functionalization of Five-Membered Heteroarenes

S Jeong, JM Joo - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Conversion of common reactants to diverse products is a key objective of
organic syntheses. Recent developments in transition-metal-catalyzed C–H functionalization …

Recent advances in functionalization of pyrroles and their translational potential

MK Hunjan, S Panday, A Gupta, J Bhaumik… - The Chemical …, 2021 - Wiley Online Library
Among the known aromatic nitrogen heterocycles, pyrrole represents a privileged aromatic
heterocycle ranging its occurrence in the key component of “pigments of life” to biologically …

Ligand-Enabled β-C(sp3)–H Olefination of Free Carboxylic Acids

Z Zhuang, CB Yu, G Chen, QF Wu… - Journal of the …, 2018 - ACS Publications
An acetyl-protected aminoethyl phenyl thioether has been developed to promote C (sp3)–H
activation. Significant ligand enhancement is demonstrated by the realization of the first Pd …