How plants sense and respond to stressful environments

J Lamers, T Van Der Meer, C Testerink - Plant Physiology, 2020 - academic.oup.com
Plants are exposed to an ever-changing environment to which they have to adjust
accordingly. Their response is tightly regulated by complex signaling pathways that all start …

Temperature sensing in plants

SM Kerbler, PA Wigge - Annual Review of Plant Biology, 2023 - annualreviews.org
Temperature is a key environmental cue that influences the distribution and behavior of
plants globally. Understanding how plants sense temperature and integrate this information …

Abiotic stress in plants; stress perception to molecular response and role of biotechnological tools in stress resistance

QM Imran, N Falak, A Hussain, BG Mun, BW Yun - Agronomy, 2021 - mdpi.com
Plants, due to their sessile nature, face several environmental adversities. Abiotic stresses
such as heat, cold, drought, heavy metals, and salinity are serious threats to plant production …

Role of TREK-1 in health and disease, focus on the central nervous system

A Djillani, J Mazella, C Heurteaux… - Frontiers in …, 2019 - frontiersin.org
TREK-1 is the most studied background K2P channel. Its main role is to control cell
excitability and maintain the membrane potential below the threshold of depolarization …

Ion channels and thermosensitivity: TRP, TREK, or both?

JA Lamas, L Rueda-Ruzafa… - International journal of …, 2019 - mdpi.com
Controlling body temperature is a matter of life or death for most animals, and in mammals
the complex thermoregulatory system is comprised of thermoreceptors, thermosensors, and …

Two-pore domain potassium channels as drug targets: anesthesia and beyond

A Mathie, EL Veale, KP Cunningham… - Annual review of …, 2021 - annualreviews.org
Two-pore domain potassium (K2P) channels stabilize the resting membrane potential of
both excitable and nonexcitable cells and, as such, are important regulators of cell activity …

[HTML][HTML] Molecular mechanisms of cold pain

DI MacDonald, JN Wood, EC Emery - Neurobiology of Pain, 2020 - Elsevier
The sensation of cooling is essential for survival. Extreme cold is a noxious stimulus that
drives protective behaviour and that we thus perceive as pain. However, chronic pain …

STIM1 and ORAI1 form a novel cold transduction mechanism in sensory and sympathetic neurons

TJ Buijs, B Vilar, CH Tan, PA McNaughton - The EMBO Journal, 2023 - embopress.org
Moderate coolness is sensed by TRPM8 ion channels in peripheral sensory nerves, but the
mechanism by which noxious cold is detected remains elusive. Here, we show that …

Nociceptor signalling through ion channel regulation via GPCRs

I Salzer, S Ray, K Schicker, S Boehm - International journal of molecular …, 2019 - mdpi.com
The prime task of nociceptors is the transformation of noxious stimuli into action potentials
that are propagated along the neurites of nociceptive neurons from the periphery to the …

Contribution of Neuronal and Glial Two‐Pore‐Domain Potassium Channels in Health and Neurological Disorders

Y Luo, L Huang, P Liao, R Jiang - Neural Plasticity, 2021 - Wiley Online Library
Two‐pore‐domain potassium (K2P) channels are widespread in the nervous system and
play a critical role in maintaining membrane potential in neurons and glia. They have been …