Overcoming barriers by local drug delivery with liposomes

SG Antimisiaris, A Marazioti, M Kannavou… - Advanced drug delivery …, 2021 - Elsevier
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Recent advancements in liposome technology

N Filipczak, J Pan, SSK Yalamarty… - Advanced drug delivery …, 2020 - Elsevier
The liposomes have continued to be well-recognized as an important nano-sized drug
delivery system with attractive properties, such a characteristic bilayer structure assembling …

Getting into the brain: liposome-based strategies for effective drug delivery across the blood–brain barrier

DB Vieira, LF Gamarra - International journal of nanomedicine, 2016 - Taylor & Francis
This review summarizes articles that have been reported in literature on liposome-based
strategies for effective drug delivery across the blood–brain barrier. Due to their unique …

Recent advances in intranasal liposomes for drug, gene, and vaccine delivery

VA Duong, TTL Nguyen, HJ Maeng - Pharmaceutics, 2023 - mdpi.com
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Quality by design-driven zeta potential optimisation study of liposomes with charge imparting membrane additives

Z Németh, I Csóka, R Semnani Jazani, B Sipos… - Pharmaceutics, 2022 - mdpi.com
Liposomal formulations, as versatile nanocarrier systems suitable for targeted delivery, have
a highly focused role in the therapy development of unmet clinical needs and diagnostic …

Advances in Parkinson's disease: 200 years later

NLG Del Rey, A Quiroga-Varela, E Garbayo… - Frontiers in …, 2018 - frontiersin.org
When James Parkinson described the classical symptoms of the disease he could hardly
foresee the evolution of our understanding over the next two hundred years. Nowadays …

Liposomal formulations for nose-to-brain delivery: recent advances and future perspectives

SS Hong, KT Oh, HG Choi, SJ Lim - Pharmaceutics, 2019 - mdpi.com
Restricted drug entry to the brain that is closely associated with the existence of the blood
brain barrier (BBB) has limited the accessibility of most potential active therapeutic …

Nose-to-brain peptide delivery–the potential of nanotechnology

E Samaridou, MJ Alonso - Bioorganic & medicinal chemistry, 2018 - Elsevier
Abstract Nose-to-brain (N-to-B) delivery offers to protein and peptide drugs the possibility to
reach the brain in a non-invasive way. This article is a comprehensive review of the state-of …

Intranasal delivery and transfection of mRNA therapeutics in the brain using cationic liposomes

HK Dhaliwal, Y Fan, J Kim, MM Amiji - Molecular Pharmaceutics, 2020 - ACS Publications
Nucleic acid-based therapeutics, including the use of messenger RNA (mRNA) as a drug
molecule, has tremendous potential in the treatment of chronic diseases, such as age …

Nanocarriers for biomedicine: From lipid formulations to inorganic and hybrid nanoparticles

R Kashapov, A Ibragimova, R Pavlov… - International Journal of …, 2021 - mdpi.com
Encapsulation of cargoes in nanocontainers is widely used in different fields to solve the
problems of their solubility, homogeneity, stability, protection from unwanted chemical and …