[HTML][HTML] Injectable hydrogels in central nervous system: Unique and novel platforms for promoting extracellular matrix remodeling and tissue engineering

E Hasanzadeh, A Seifalian, A Mellati, J Saremi… - Materials Today Bio, 2023 - Elsevier
Repairing central nervous system (CNS) is difficult due to the inability of neurons to recover
after damage. A clinically acceptable treatment to promote CNS functional recovery and …

Hydrogel and nanomedicine‐based multimodal therapeutic strategies for spinal cord injury

P Yin, W Liang, B Han, Y Yang, D Sun, X Qu… - Small …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a severe neurodegenerative disease caused by mechanical and
biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury …

Application of injectable hydrogels as delivery Systems in Spinal Cord Injury

R Ji, Z Hao, H Wang, X Li, L Duan, F Guan, S Ma - Gels, 2023 - mdpi.com
Spinal cord injury (SCI) is a severe neurological injury caused by traffic accidents, trauma, or
falls, which leads to significant loss of sensory, motor, and autonomous functions and …

Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement

PH Lin, Q Dong, SY Chew - Materials Advances, 2021 - pubs.rsc.org
Central nervous system (CNS) pathologies, such as stroke and spinal cord injury, remain
debilitating issues due to the inhibitory environment in the CNS. Many research works have …

Supporting wound healing by mesenchymal stem cells (MSCs) therapy in combination with scaffold, hydrogel, and matrix; State of the art

BI Sukmana, R Margiana, YQ Almajidi… - … -Research and Practice, 2023 - Elsevier
Non-healing wounds impose a huge annual cost on the survival of different countries and
large populations in the world. Wound healing is a complex and multi-step process, the …

Injectable Hydrogels for Nervous Tissue Repair—A Brief Review

GA Politrón-Zepeda, G Fletes-Vargas… - Gels, 2024 - mdpi.com
The repair of nervous tissue is a critical research field in tissue engineering because of the
degenerative process in the injured nervous system. In this review, we summarize the …

[HTML][HTML] Human-derived cytokine functionalized sericin/agarose composite gel material with cell proliferation-promoting activity fabricated using genetically …

Y Wang, F Wang, R Wang, C Tian, X Hua, P Zhao… - Materials & Design, 2022 - Elsevier
Functional biomaterials have great potential for future medical application. Although
functional biomaterials produced from genetically engineered silk are promising, it can be …

Reverse adverse immune microenvironments by biomaterials enhance the repair of spinal cord injury

H Wang, Y Xia, B Li, Y Li, C Fu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Spinal cord injury (SCI) is a severe and traumatic disorder that ultimately results in the loss
of motor, sensory, and autonomic nervous function. After SCI, local immune inflammatory …

Advances in Injectable Polymeric Biomaterials and Their Contemporary Medical Practices

S Beilharz, MK Debnath, D Vinella… - ACS Applied Bio …, 2024 - ACS Publications
Injectable biomaterials have been engineered to operate within the human body, offering
versatile solutions for minimally invasive therapies and meeting several stringent …

Silk-elastin-like polymers for acute intraparenchymal treatment of the traumatically injured spinal cord: a first systematic experimental approach

P González, C González-Fernández, A Maqueda… - Pharmaceutics, 2022 - mdpi.com
Despite the promising potential of hydrogel-based therapeutic approaches for spinal cord
injury (SCI), the need for new biomaterials to design effective strategies for SCI treatment …