Full-field optical coherence tomography as a diagnosis tool: recent progress with multimodal imaging

O Thouvenin, C Apelian, A Nahas, M Fink, C Boccara - Applied Sciences, 2017 - mdpi.com
Full-field optical coherence tomography (FF-OCT) is a variant of OCT that is able to register
2D en face views of scattering samples at a given depth. Thanks to its superior resolution, it …

En face coherence microscopy

O Thouvenin, K Grieve, P Xiao, C Apelian… - Biomedical optics …, 2017 - opg.optica.org
En face coherence microscopy or flying spot or full field optical coherence tomography or
microscopy (FF-OCT/FF-OCM) belongs to the OCT family because the sectioning ability is …

[HTML][HTML] Three-dimensional structure of the mammalian limbal stem cell niche

K Grieve, D Ghoubay, C Georgeon, O Thouvenin… - Experimental eye …, 2015 - Elsevier
Although the existence of the limbal stem cell (LSC) niche is accepted, precise knowledge of
its three-dimensional (3D) architecture remains incomplete. The LSC niche was explored on …

Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT

J Scholler, V Mazlin, O Thouvenin, K Groux… - Biomedical optics …, 2019 - opg.optica.org
We describe recent technological progress in multimodal en face full-field optical coherence
tomography that has allowed detection of slow and fast dynamic processes in the eye. We …

[HTML][HTML] Cell motility as contrast agent in retinal explant imaging with full-field optical coherence tomography

O Thouvenin, C Boccara, M Fink… - … & visual science, 2017 - tvst.arvojournals.org
Methods: Macaque and mouse retinal explants were imaged with high resolution full field
optical coherence tomography (FFOCT) and dynamic FFOCT, coupled with fluorescence …

Dynamic multimodal full-field optical coherence tomography and fluorescence structured illumination microscopy

O Thouvenin, M Fink, C Boccara - Journal of Biomedical Optics, 2017 - spiedigitallibrary.org
We report on the development of a configuration of a multimodal full-field optical coherence
tomography (FF-OCT) and fluorescence microscope. Our system can simultaneously …

Noninvasive detection of metastases and follicle density in ovarian tissue using full-field optical coherence tomography

ITA Peters, PL Stegehuis, R Peek, FL Boer… - Clinical cancer …, 2016 - AACR
Purpose: Autotransplantation of ovarian tissue can be used to restore fertility in patients with
cancer following gonadotoxic treatment. Whether this procedure is safe remains unclear, as …

[HTML][HTML] Appearance of the retina with full-field optical coherence tomography

K Grieve, O Thouvenin, A Sengupta… - … & visual science, 2016 - tvst.arvojournals.org
Methods: Flatmounted retinas of human, primate, pig, sheep, rat, and mouse were imaged
using FFOCT. To identify retinal ganglion and amacrine cells, fixed samples immunolabeled …

[HTML][HTML] Full-field optical coherence tomography for the analysis of fresh unstained human lobectomy specimens

M Jain, N Narula, B Salamoon, MM Shevchuk… - Journal of pathology …, 2013 - Elsevier
Background: Full-field optical coherence tomography (FFOCT) is a real-time imaging
technique that generates high-resolution three-dimensional tomographic images from …

Rapid pseudo-H&E imaging using a fluorescence-inbuilt optical coherence microscopic imaging system

SE Lin, DY Jheng, KY Hsu, YR Liu… - Biomedical Optics …, 2021 - opg.optica.org
A technique using Linnik-based optical coherence microscopy (OCM), with built-in
fluorescence microscopy (FM), is demonstrated here to describe cellular-level morphology …