Within the last decade, the application range of aptamers in biochemistry and medicine has
expanded rapidly. More than just a replacement for antibodies, these intrinsically structured …

Abstract Polysorbate (PS) 20 and 80 are the main surfactants used to stabilize
biopharmaceutical products. Industry practices on various aspects of PS based on a …

Detection of cancer markers is important for early diagnosis and timely treatment of cancer.
In this study, we fabricated a tailorable gold nanofilm-anodized aluminum oxide (Au-AAO) …

Natural killer (NK) cells are a key component of the innate immune system as they can attack
cancer cells without prior sensitization. However, due to lack of cell‐specific receptors, NK …

Flow cytometry is a powerful tool for analyzing cellular phenotypes in a large population of
cells, and it is commonly used in many applications from basic research to clinical practice …

Host cell proteins (HCPs) are process‐related impurities in a therapeutic protein expressed
using cell culture technology. This review presents biopharmaceutical industry trends in …

In this work, the boronic acid–aptamer conjugate (BAAC) is elaborately designed and
explored as a recognition unit. The admirable properties of the pH-dependent boronic acid …

Consequently, it is a regulatory requirement to monitor HCP impurities in therapeutic mAbs
using sensitive analytical methods. LC-MS/MS is a powerful method that facilitates both …