[HTML][HTML] An overview of pharmacological activities of baicalin and its aglycone baicalein: New insights into molecular mechanisms and signaling pathways

Z Hu, Y Guan, W Hu, Z Xu, M Ishfaq - Iranian Journal of Basic …, 2022 - ncbi.nlm.nih.gov
The flavonoids, baicalin, and its aglycone baicalein possess multi-fold therapeutic properties
and are mainly found in the roots of Oroxylum indicum (L.) Kurz and Scutellaria baicalensis …

[HTML][HTML] Current status of vaccine research, development, and challenges of vaccines for Mycoplasma gallisepticum

M Ishfaq, W Hu, MZ Khan, I Ahmad, W Guo, J Li - Poultry science, 2020 - Elsevier
Mycoplasma gallisepticum (MG) is an important avian pathogen that causes significant
economic losses in the poultry industry. Surprisingly, the limited protection and adverse …

[HTML][HTML] The effect of ammonia exposure on energy metabolism and mitochondrial dynamic proteins in chicken thymus: through oxidative stress, apoptosis, and …

SWA Shah, D Chen, J Zhang, Y Liu, M Ishfaq… - Ecotoxicology and …, 2020 - Elsevier
Ammonia (NH 3) gas is an atmospheric pollutant, produced from different sources. In poultry
houses NH 3 is produced from the biological process of liter, manure, and protein …

Redox homeostasis in poultry: regulatory roles of NF-κB

PF Surai, II Kochish, MT Kidd - Antioxidants, 2021 - mdpi.com
Redox biology is a very quickly developing area of modern biological sciences, and roles of
redox homeostasis in health and disease have recently received tremendous attention …

Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway

M Ishfaq, Z Wu, J Wang, R Li, C Chen, J Li - International …, 2021 - Elsevier
Baicalin is a well-known flavonoid compound, possess therapeutic potential against
inflammatory diseases. Previous studies reported that Mycoplasma gallisepticum (MG) …

[HTML][HTML] PTEN/AKT/mTOR pathway involvement in autophagy, mediated by miR-99a-3p and energy metabolism in ammonia-exposed chicken bursal lymphocytes

SWA Shah, S Zhang, M Ishfaq, Y Tang, X Teng - Poultry science, 2021 - Elsevier
Emission of atmospheric ammonia (NH 3) is an environmental challenge because of its
harmful effects on humans and animals including birds. Among all organisms, NH 3 is highly …

Extracellular HMGB1 as inflammatory mediator in the progression of mycoplasma gallisepticum infection

Y Wang, L Wang, F Hu, M Zou, R Luo, Y Sun, T Wang… - Cells, 2022 - mdpi.com
High-mobility group box 1 (HMGB1), a member of damage-associated molecular patterns
(DAMPs), is involved in the immune regulation of several infectious diseases. Mycoplasma …

Baicalin attenuated Mycoplasma gallisepticum‐induced immune impairment in chicken bursa of fabricius through modulation of autophagy and inhibited …

M Ishfaq, W Zhang, Y Liu, J Wang, Z Wu… - Journal of the …, 2021 - Wiley Online Library
BACKGROUND Mycoplasma gallisepticum (MG) is the primary etiologic agent of chronic
respiratory disease in poultry. However, the mechanism underlying MG‐induced immune …

Mycoplasma gallisepticum infection triggered histopathological changes, oxidative stress and apoptosis in chicken thymus and spleen

W Hu, W Zhang, SWA Shah, M Ishfaq, J Li - Developmental & Comparative …, 2021 - Elsevier
Previous studies mainly focused on the inflammatory responses caused by Mycoplasma
gallisepticum (MG) in the chicken respiratory mucosa, setting the stage for chronic infection …

Polydatin attenuates Mycoplasma gallisepticum (HS strain)-induced inflammation injury via inhibiting the TLR6/MyD88/NF-κB pathway

M Zou, W Yang, L Niu, Y Sun, R Luo, Y Wang… - Microbial …, 2020 - Elsevier
Mycoplasma gallisepticum (MG) infection is the main cause of chronic respiratory disease
(CRD) characterized by severe respiratory inflammation in chickens. Polydatin (PD) is a …