Development of therapeutic proteins: advances and challenges

MSH Akash, K Rehman, M Tariq… - Turkish Journal of …, 2015 - journals.tubitak.gov.tr
Therapeutic proteins have shown to be effective against a variety of diseases.
Pharmaceutical companies are progressively focusing on research using proteins in search …

Relationship between hepatic progenitor cell‐mediated liver regeneration and non‐parenchymal cells

M Kitade, K Kaji, H Yoshiji - Hepatology Research, 2016 - Wiley Online Library
Hepatic progenitor cells (HPCs) are thought to reside in the canals of Hering and can be
activated and contribute to liver regeneration in response to liver injury by proliferating and …

Hepatoprotective effects of Malva sylvestris L. against paracetamol-induced hepatotoxicity

L Hussain, J Ikram, K Rehman, M Tariq… - Turkish Journal of …, 2014 - journals.tubitak.gov.tr
Malva sylvestris is traditionally used for the treatment of liver diseases, but sufficient
pharmacological-based scientific literature is not available online to authenticate its use in …

Hepatoprotective effects of methanolic extract of Alcea rosea against acetaminophen-induced hepatotoxicity in mice

L Hussain, MSH Akash, M Tahir… - ||| Bangladesh …, 2014 - bdpsjournal.org
The aim of this study was to evaluate the hepatoprotective effects of Alcea rosea against
acetaminophen-induced hepatotoxicity in mice. Aqueous methanolic extract of A. rosea …

Ectopic osteoid and bone formation by three calcium-phosphate ceramics in rats, rabbits and dogs

L Wang, B Zhang, C Bao, P Habibovic, J Hu, X Zhang - PloS one, 2014 - journals.plos.org
Calcium phosphate ceramics with specific physicochemical properties have been shown to
induce de novo bone formation upon ectopic implantation in a number of animal models. In …

Human CD34loCD133lo fetal liver cells support the expansion of human CD34hiCD133hi hematopoietic stem cells

KSM Yong, CT Keng, SQ Tan, E Loh… - Cellular & molecular …, 2016 - nature.com
We have recently discovered a unique CD34 lo CD133 lo cell population in the human fetal
liver (FL) that gives rise to cells in the hepatic lineage. In this study, we further characterized …

Methods to increase future liver remnant volume in patients with primarily unresectable colorectal liver metastases: current state and future perspectives

V Treska - Anticancer research, 2016 - ar.iiarjournals.org
Radical liver resection of colorectal liver metastases (CLMs) is the only potentially curative
treatment. But primary resectability of CLMs ranges from 15% to 20%. Insufficient future liver …

[HTML][HTML] The involving roles of intrahepatic and extrahepatic stem/progenitor cells (SPCs) to liver regeneration

W Liu, L Ren, T Wang, N Navarro-Alvarez… - International journal of …, 2016 - ncbi.nlm.nih.gov
Liver regeneration is usually attributed to mature hepatocytes, which possess a remarkable
potential to proliferate under mild to moderate injury. However, when the liver is severely …

[HTML][HTML] Clinical application of stem cell in patients with end-stage liver disease: progress and challenges

YC Tao, EQ Chen - Annals of Translational Medicine, 2020 - ncbi.nlm.nih.gov
End-stage liver disease (ESLD) is life-threatening disease worldwide, and patients with
ESLD should be referred to liver transplantation (LT). However, the use of LT is limited by …

[HTML][HTML] Role of liver stem cells in hepatocarcinogenesis

LB Xu, C Liu - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
Liver cancer is an aggressive disease with a high mortality rate. Management of liver cancer
is strongly dependent on the tumor stage and underlying liver disease. Unfortunately, most …