Epithelial-mesenchymal transition (EMT): the type-2 EMT in wound healing, tissue regeneration and organ fibrosis

GD Marconi, L Fonticoli, TS Rajan, SD Pierdomenico… - Cells, 2021 - mdpi.com
The epithelial–mesenchymal transition (EMT) is an essential event during cell development,
in which epithelial cells acquire mesenchymal fibroblast-like features including reduced …

Versatile polyphenolic platforms in regulating cell biology

H Cao, L Yang, R Tian, H Wu, Z Gu, Y Li - Chemical Society Reviews, 2022 - pubs.rsc.org
Polyphenolic materials are a class of fascinating and versatile bioinspired materials for
biointerfacial engineering. In particular, due to the presence of active chemical groups, a …

Recent progress in biopolymer-based hydrogel materials for biomedical applications

A Mahmood, D Patel, B Hickson… - International Journal of …, 2022 - mdpi.com
Hydrogels from biopolymers are readily synthesized, can possess various characteristics for
different applications, and have been widely used in biomedicine to help with patient …

In-situ growth of robust superlubricated nano-skin on electrospun nanofibers for post-operative adhesion prevention

Y Wang, Y Xu, W Zhai, Z Zhang, Y Liu, S Cheng… - Nature …, 2022 - nature.com
It is a great challenge to achieve robustly bonded, fully covered, and nanoscaled coating on
the surface of electrospun nanofibers. Herein, we develop a controllable, facile, and …

Additive manufacturing of precision biomaterials

EA Guzzi, MW Tibbitt - Advanced materials, 2020 - Wiley Online Library
Biomaterials play a critical role in modern medicine as surgical guides, implants for tissue
repair, and as drug delivery systems. The emerging paradigm of precision medicine exploits …

Epithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities

Z Huang, Z Zhang, C Zhou, L Liu, C Huang - MedComm, 2022 - Wiley Online Library
Epithelial–mesenchymal transition (EMT) is a program wherein epithelial cells lose their
junctions and polarity while acquiring mesenchymal properties and invasive ability …

Reshaping the tumor stroma for treatment of pancreatic cancer

C Vennin, KJ Murphy, JP Morton, TR Cox, M Pajic… - Gastroenterology, 2018 - Elsevier
Pancreatic cancer is accompanied by a fibrotic reaction that alters interactions between
tumor cells and the stroma to promote tumor progression. Consequently, strategies to target …

Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate

TC von Erlach, S Bertazzo, MA Wozniak, CM Horejs… - Nature materials, 2018 - nature.com
Cell size and shape affect cellular processes such as cell survival, growth and
differentiation,,–, thus establishing cell geometry as a fundamental regulator of cell …

Harnessing the secreted extracellular matrix to engineer tissues

U Blache, MM Stevens, E Gentleman - Nature biomedical engineering, 2020 - nature.com
Harnessing the secreted extracellular matrix to engineer tissues | Nature Biomedical Engineering
Skip to main content Thank you for visiting nature.com. You are using a browser version with …

Scarring vs. functional healing: Matrix-based strategies to regulate tissue repair

TJ Keane, CM Horejs, MM Stevens - Advanced drug delivery reviews, 2018 - Elsevier
All vertebrates possess mechanisms to restore damaged tissues with outcomes ranging
from regeneration to scarring. Unfortunately, the mammalian response to tissue injury most …