Antioxidants maintain cellular redox homeostasis by elimination of reactive oxygen species

L He, T He, S Farrar, L Ji, T Liu, X Ma - Cellular Physiology and …, 2017 - karger.com
Reactive oxygen species (ROS) are produced by living cells as normal cellular metabolic
byproduct. Under excessive stress conditions, cells will produce numerous ROS, and the …

The role of resveratrol in cancer therapy

JH Ko, G Sethi, JY Um, MK Shanmugam… - International journal of …, 2017 - mdpi.com
Natural product compounds have recently attracted significant attention from the scientific
community for their potent effects against inflammation-driven diseases, including cancer. A …

Polyphenols: From theory to practice

A Bertelli, M Biagi, M Corsini, G Baini, G Cappellucci… - Foods, 2021 - mdpi.com
Background: The importance of polyphenols in human health is well known; these
compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and …

The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress

J Limón-Pacheco, ME Gonsebatt - Mutation Research/Genetic Toxicology …, 2009 - Elsevier
In aerobic organisms, oxygen is essential for efficient energy production but paradoxically,
produces chronic toxic stress in cells. Diverse protective systems must exist to enable …

Cancer chemopreventive and therapeutic potential of resveratrol: mechanistic perspectives

JK Kundu, YJ Surh - Cancer letters, 2008 - Elsevier
A plant kingdom is considered as a gold mine for the discovery of many biologically active
substances with therapeutic values. Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally …

Resveratrol and its analogs: defense against cancer, coronary disease and neurodegenerative maladies or just a fad?

P Saiko, A Szakmary, W Jaeger, T Szekeres - Mutation Research/Reviews …, 2008 - Elsevier
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene; RV), a dietary constituent found in grapes
and wine, exerts a wide variety of pharmacological activities. Because the grape skins are …

Resveratrol modulates drug-and carcinogen-metabolizing enzymes in a healthy volunteer study

HHS Chow, LL Garland, CH Hsu, DR Vining… - Cancer prevention …, 2010 - AACR
Resveratrol has been shown to exhibit cancer-preventive activities in preclinical studies. We
conducted a clinical study to determine the effect of pharmacologic doses of resveratrol on …

Resveratrol: its biologic targets and functional activity

S Pervaiz, AL Holme - Antioxidants & redox signaling, 2009 - liebertpub.com
Abstract 2852 The polyphenolic phytoalexin resveratrol (RSV) and its analogues have
received tremendous attention over the past couple of decades because of a number of …

Therapeutic approaches of resveratrol on endometriosis via anti-inflammatory and anti-angiogenic pathways

AM Dull, MA Moga, OG Dimienescu, G Sechel… - Molecules, 2019 - mdpi.com
Endometriosis represents a severe gynecological pathology, defined by implantation of
endometrial glands and stroma outside the uterine cavity. This pathology affects almost 15 …

Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer

D Delmas, A Lançon, D Colin, B Jannin… - Current drug …, 2006 - ingentaconnect.com
Resveratrol (3, 4', 5 tri-hydroxystilbene) is a phytoalexin produced in hudge amount in
grapevine skin in response to infection by Bothrytis cinerea. This production of resveratrol …