In 2016, a group of researchers engaged in the development of patient-derived xenografts
(PDXs) of human breast cancer provided a comprehensive review of the state of the field. In …

The activation of anti-tumor immunity is critical in treating cancers. Recent studies indicate
that several chemotherapy agents can stimulate anti-tumor immunity by inducing …

Ferroptosis and apoptosis are key cell‐death pathways implicated in several human
diseases including cancer. Ferroptosis is driven by iron‐dependent lipid peroxidation and …

Multiple cancers exhibit aberrant protein arginine methylation by both type I arginine
methyltransferases, predominately protein arginine methyltransferase 1 (PRMT1) and to a …

The availability of high-fidelity animal models for oncology research has grown enormously
in recent years, enabling preclinical studies relevant to prevention, diagnosis, and treatment …

Gastric cancer is a leading cause of cancer-related deaths globally and chemotherapy is
widely accepted as the standard treatment for gastric cancer. However, drug resistance in …

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous cancer with high
morbidity and mortality. Triggering the programmed cell death (PCD) to enhance the anti …

Background Conjugation of transferrin (Tf) to imaging or nanotherapeutic agents is a
promising strategy to target breast cancer. Since the efficacy of these biomaterials often …

Due to variability in pharmacokinetics and pharmacodynamics, clinical outcomes of
antimicrobial drug therapy vary between patients. As such, personalised medication …

It would be highly desirable to find prognostic and predictive markers for triple-negative
breast cancer (TNBC), a strongly heterogeneous and invasive breast cancer subtype often …