Integrins expressed on extracellular vesicles (EVs) secreted by various cancers are reported
to mediate the organotropism of these EVs. Our previous experiment found that pancreatic …

Corona Virus Disease 2019 (COVID-19), an acute respiratory infectious disease caused by
severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread rapidly …

Immune system recognizes invading microbes at both pathogen and antigen levels. Toll-like
receptors (TLRs) play a key role in the first-line defense against pathogens. Major functions …

To utilize metabolomics in conjunction with RNA sequencing to identify biomarkers in the
blood of sepsis patients and discover novel targets for diagnosing and treating sepsis. In …

Extracellular vesicles (EVs) have been identified as cell‐cell communication agents, and
EVs derived from mesenchymal stem cells (MSCs) exhibit therapeutic effects similar to those …

The role of Neutrophil extracellular traps (NETs) in the immunopathogenesis of Diabetic
Kidney Disease (DKD) remains elusive. We used a machine learning approach to identify …

Sepsis is a leading cause of morbidity and mortality in the intensive care unit, which is
caused by unregulated inflammatory response leading to organ injuries. Ulinastatin (UTI) …

The herbal plant Angelica gigas (A. gigas) has been used in traditional medicine in East
Asian countries, and its chemical components are reported to have many pharmacological …

Background Programmed cell death (PCD) has emerged as a pivotal progress in
pathogenesis of sepsis, but its role in identification of sepsis has not been fully understood …

In gout, monosodium urate crystals are taken up by macrophages, triggering the activation of
the NLRP3 inflammasome and the maturation of IL-1β. This study aimed to investigate the …