In the regulation of behavior, the role of GABA neurons has been extensively studied in the
circuit of fear, where GABA interneurons play key parts in the acquisition, storage and …

Intellectual disability, autism spectrum disorder, and epilepsy are prime examples of
neurodevelopmental disorders that collectively affect a significant percentage of the world …

The fundamental principle that unites addictive drugs appears to be that each enhances
synaptic dopamine by means that dissociate it from normal behavioral control, so that they …

In the past 20 years we have learned a great deal about GABA A receptor (GABA AR)
subtypes, and which behaviors are regulated or which drug effects are mediated by each …

Isoxazolines are a novel class of parasiticides that are potent inhibitors of γ-aminobutyric
acid (GABA)-gated chloride channels (GABACls) and l-glutamate-gated chloride channels …

GABA A receptors are pentameric ligand-gated ion channels that mediate most fast
neuronal inhibition in the brain. In addition to their important physiological roles, they are …

GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the
main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and …

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability and the
leading monogenic cause of autism. The condition stems from loss of fragile X mental …

Background Over the past several decades, complementary and alternative medications
have increasingly become a part of everyday treatment. With the rising cost of prescription …

Long-term potentiation (LTP) in nociceptive spinal pathways shares several features with
hyperalgesia and has been proposed to be a cellular mechanism of pain amplification in …