[HTML][HTML] Herpesvirus latency

JI Cohen - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
Herpesviruses infect virtually all humans and establish lifelong latency and reactivate to
infect other humans. Latency requires multiple functions: maintaining the herpesvirus …

[HTML][HTML] Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response

E Forte, Z Zhang, EB Thorp, M Hummel - Frontiers in cellular and …, 2020 - frontiersin.org
CMV is an ancient herpesvirus that has co-evolved with its host over millions of years. The
236 kbp genome encodes at least 165 genes, four non-coding RNAs and 14 miRNAs. Of the …

[HTML][HTML] Chronic viral coinfections differentially affect the likelihood of developing long COVID

MJ Peluso, TM Deveau, SE Munter… - The Journal of …, 2023 - Am Soc Clin Investig
BACKGROUND The presence and reactivation of chronic viral infections, such as EBV,
CMV, and HIV, have been proposed as potential contributors to long COVID (LC), but …

[PDF][PDF] Host-viral infection maps reveal signatures of severe COVID-19 patients

P Bost, A Giladi, Y Liu, Y Bendjelal, G Xu, E David… - Cell, 2020 - cell.com
Viruses are a constant threat to global health as highlighted by the current COVID-19
pandemic. Currently, lack of data underlying how the human host interacts with viruses …

[HTML][HTML] Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy

E Wyler, K Mösbauer, V Franke, A Diag, LT Gottula… - IScience, 2021 - Elsevier
Detailed knowledge of the molecular biology of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host …

[HTML][HTML] The relationship between the gut microbiome and host gene expression: a review

RG Nichols, ER Davenport - Human genetics, 2021 - Springer
Despite the growing knowledge surrounding host–microbiome interactions, we are just
beginning to understand how the gut microbiome influences—and is influenced by—host …

[PDF][PDF] Dissection of influenza infection in vivo by single-cell RNA sequencing

Y Steuerman, M Cohen, N Peshes-Yaloz, L Valadarsky… - Cell systems, 2018 - cell.com
The influenza virus is a major cause of morbidity and mortality worldwide. Yet, both the
impact of intracellular viral replication and the variation in host response across different cell …

[HTML][HTML] Single-cell RNA-seq methods to interrogate virus-host interactions

K Ratnasiri, AJ Wilk, MJ Lee, P Khatri… - Seminars in …, 2023 - Springer
The twenty-first century has seen the emergence of many epidemic and pandemic viruses,
with the most recent being the SARS-CoV-2-driven COVID-19 pandemic. As obligate …

[HTML][HTML] Human cytomegalovirus latency and reactivation in allogeneic hematopoietic stem cell transplant recipients

L Stern, B Withers, S Avdic, D Gottlieb… - Frontiers in …, 2019 - frontiersin.org
Human cytomegalovirus (HCMV) reactivation is a major infectious cause of morbidity and
mortality after allogeneic hematopoietic stem cell transplantation (HSCT). HCMV is a …

[HTML][HTML] Single-cell RNA sequencing with spatial transcriptomics of cancer tissues

R Ahmed, T Zaman, F Chowdhury, F Mraiche… - International journal of …, 2022 - mdpi.com
Single-cell RNA sequencing (RNA-seq) techniques can perform analysis of transcriptome at
the single-cell level and possess an unprecedented potential for exploring signatures …