C Harrington, S Krishnan, CL Mack, P Cravedi… - …, 2022 - Wiley Online Library
Autoimmune hepatitis (AIH) is a rare disease of unclear etiology characterized by loss of self‐ tolerance that can lead to liver injury, cirrhosis, and acute liver failure. First‐line treatment …
WJ Armitage, C Goodchild, MD Griffin, DJ Gunn… - …, 2019 - journals.lww.com
Human corneal transplantation (keratoplasty) is typically considered to have superior short- and long-term outcomes and lower requirement for immunosuppression compared to solid …
Progress in renal transplantation requires improved understanding and assessment of rejection and injury. Study of the relationship between gene expression and clinical …
Noninvasive biomarkers are needed to monitor stable patients after kidney transplant (KT), because subclinical acute rejection (subAR), currently detectable only with surveillance …
Background Immunosuppression nonadherence increases the risk for kidney transplant loss after transplantation. Wireless-enabled pill bottles have created the opportunity to monitor …
S Park, K Guo, RL Heilman, ED Poggio… - Clinical Journal of the …, 2021 - journals.lww.com
Results For diagnosing subclinical rejection, the gene expression profile demonstrated a negative predictive value of 82%, a positive predictive value of 47%, a balanced accuracy of …
Background Sepsis involves aberrant immune responses to infection, but the exact nature of this immune dysfunction remains poorly defined. Bacterial endotoxins like …
E Van Loon, S Gazut, S Yazdani, E Lerut, H de Loor… - …, 2019 - thelancet.com
Background Antibody-mediated rejection, a leading cause of renal allograft graft failure, is diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive …
M Naesens, D Anglicheau - Journal of the American Society of …, 2018 - journals.lww.com
The concept that individuals with the same disease and a similar clinical presentation may have very different outcomes and need very different therapies is not novel. With the …