The discovery in 1961 of a catalytic activity for the addition of glutathione (GSH) to 1, 2-
dichloro-4-nitrobenzene in cytosolic extracts of liver (1, 2) initiated three decades of …

The glutathione transferases (GSTs) are one of the most important families of detoxifying
enzymes in nature. The classic activity of the GSTs is conjugation of compounds with …

A new class of glutathione transferases has been discovered by analysis of the expressed
sequence tag data base and sequence alignment. Glutathione S-transferases (GSTs) of the …

Glutathione transferases (GSTs) are important detoxifying enzymes that catalyze the
conjugation of electrophilic substrates to glutathione. In recent years, GSTs have been of …

Previous studies have identified allelic variants of the human glutathione transferase (GST)
Pi gene and showed that the two different encoded proteins with isoleucine (GSTP1-1/I-105) …

Hematopoietic prostaglandin (PG) D synthase is the key enzyme for production of the D and
J series of prostanoids in the immune system and mast cells. We isolated a cDNA for the rat …

The aquatic environment is generally affected by the presence of environmental xenobiotic
compounds. One of the major xenobiotic detoxifying enzymes is glutathione S-transferase …

Many people who are interested in biology are still under the impression that the beautiful
pictures of macromolecules presented in this journal and others are to be believed down to …

We have previously shown that nitric oxide (NO) inhibits growth and induces differentiation
and apoptosis in acute myeloid leukemia cells, with the HL-60 human myeloid leukemia line …

The catalytic activity of human glutathione S‐transferase A1‐1 (hGSTA1‐1), a homodimeric
detoxification enzyme, is dependent on the conformational dynamics of a key C‐terminal …