[HTML][HTML] The landscape of small leucine-rich proteoglycan impact on cancer pathogenesis with a focus on biglycan and lumican

A Berdiaki, EM Giatagana, G Tzanakakis, D Nikitovic - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a complex disease in which both cells and their environment are
altered. A tumor microenvironment contains tumor cells, normal tissue cells, blood vessels …

The functional network of biglycan: A new frontier in tumor progression

L Yu, N Maishi, A Matsuda, K Hida - Proteoglycan Research, 2023 - Wiley Online Library
Biglycan is a member of the small leucine‐rich proteoglycan family. Dysregulation of
biglycan leads to a broad range of clinical consequences, such as osteoclastogenesis …

Genomic alterations in ovarian endometriosis and subsequently diagnosed ovarian carcinoma

A Linder, S Westbom-Fremer, C Mateoiu… - Human …, 2024 - academic.oup.com
STUDY QUESTION Can the alleged association between ovarian endometriosis and
ovarian carcinoma be substantiated by genetic analysis of endometriosis diagnosed prior to …

[HTML][HTML] Correlation of the tumor escape phenotype with loss of PRELP expression in melanoma

H Schäfer, K Subbarayan, C Massa… - Journal of Translational …, 2023 - Springer
Background Despite immunotherapies having revolutionized the treatment of advanced
cutaneous melanoma, effective and durable responses were only reported in a few patients …

Identification of ROS and KEAP1‐related genes and verified targets of α‐hederin induce cell death for CRC

G Wang, ZM Zhu, K Wang - Drug Development Research, 2024 - Wiley Online Library
In this study, we analyzed and verified differentially expressed genes (DEGs) in ROS and
KEAP1 crosstalk in oncogenic signatures using GEO data sets (GSE4107 and GSE41328) …

Identification and verification of KEAP1‐related genes and targets regulated by potential ingredients in KRAS mutant colorectal cancer

G Wang, F Li, ZM Zhu, K Wang… - Precision Medical …, 2023 - Wiley Online Library
As one of the most prevalent tumors, colorectal cancer (CRC) owns complex pathogenesis
and the high recurrence rate significantly influence the prognosis of patients with KRAS …