Vitamin D and the nervous system

G Bivona, CM Gambino, G Iacolino… - Neurological …, 2019 - Taylor & Francis
Objective: to summarise the activities that Vitamin D (VD) carries out in the brain and to
clarify the potential role of VD in neurological diseases. Methods: a literature research has …

Vitamin D and genetic susceptibility to multiple sclerosis

C Scazzone, L Agnello, G Bivona, B Lo Sasso… - Biochemical …, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

Mendelian randomization study updates the effect of 25-hydroxyvitamin D levels on the risk of multiple sclerosis

R Wang - Journal of translational medicine, 2022 - Springer
Background Observational studies and previous Mendelian randomization (MR) studies
have shown that genetically low 25-hydroxyvitamin D (25OHD) levels are associated with a …

The immunological implication of the new vitamin D metabolism

G Bivona, L Agnello, M Ciaccio - Central European Journal of …, 2018 - termedia.pl
Abstract vitamin D is a neuro-hormone regulating calcium-phosphate homeostasis, cell
proliferation, and immunomodulation. exogenous and endogenous vitamin D is inactive …

Non-skeletal activities of vitamin D: from physiology to brain pathology

G Bivona, L Agnello, C Bellia, G Iacolino, C Scazzone… - Medicina, 2019 - mdpi.com
Vitamin D is a secosteroid hormone regulating the expression of almost 900 genes, and it is
involved in the regulation of calcium and phosphate metabolism, immune response, and …

[HTML][HTML] A review of the critical role of vitamin D axis on the immune system

G Daryabor, N Gholijani, FR Kahmini - Experimental and Molecular …, 2023 - Elsevier
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …

Cerebrospinal fluid analysis in multiple sclerosis diagnosis: an update

B Lo Sasso, L Agnello, G Bivona, C Bellia, M Ciaccio - Medicina, 2019 - mdpi.com
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous
system (CNS) with brain neurodegeneration. MS patients present heterogeneous clinical …

Standardized measurement of circulating vitamin D [25 (OH) D] and its putative role as a serum biomarker in Alzheimer's disease and Parkinson's disease

G Bivona, BL Sasso, G Iacolino, CM Gambino… - Clinica Chimica …, 2019 - Elsevier
The current review provides an overview on the development of 25 (OH) D measurement
standardization tools over the last three decades and clarifies whether there is a role as a …

Environmental influencers, microRNA, and multiple sclerosis

EMA Mohammed - Journal of central nervous system …, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is a complex neurological disorder characterized by an aberrant
immune system that affects patients' quality of life. Several environmental factors have …

[HTML][HTML] A Comprehensive Examination of the Role of Epigenetic Factors in Multiple Sclerosis

I Manna, S De Benedittis, D Porro - International Journal of Molecular …, 2024 - mdpi.com
According to various research, the risk of multiple sclerosis (MS) is strongly influenced by
genetic variations. Population, familial, and molecular studies provide strong empirical …