Endothelial cell dysfunction: a key determinant for the outcome of allogeneic stem cell transplantation

T Luft, P Dreger, A Radujkovic - Bone Marrow Transplantation, 2021 - nature.com
Allogeneic hematopoietic stem cell transplantation (alloSCT) carries the promise of cure for
many malignant and non-malignant diseases of the lympho-hematopoietic system. Although …

Vascular endothelial senescence: pathobiological insights, emerging long noncoding RNA targets, challenges and therapeutic opportunities

X Sun, MW Feinberg - Frontiers in Physiology, 2021 - frontiersin.org
Cellular senescence is a stable form of cell cycle arrest in response to various stressors.
While it serves as an endogenous pro-resolving mechanism, detrimental effects ensue when …

The miR‐126‐5p and miR‐212‐3p in the extracellular vesicles activate monocytes in the early stage of radiation‐induced vascular inflammation implicated in …

YY Choi, A Kim, Y Lee, YH Lee, M Park… - Journal of …, 2023 - Wiley Online Library
People exposed to radiation in cancer therapy and nuclear accidents are at increased risk of
cardiovascular outcomes in long‐term survivors. Extracellular vesicles (EVs) are involved in …

[HTML][HTML] An indispensable tool: Exosomes play a role in therapy for radiation damage

S Li, L Shao, T Xu, X Jiang, G Yang, L Dong - Biomedicine & …, 2021 - Elsevier
Radiotherapy is one of the three main treatments for tumors. Almost 70% of tumor patients
undergo radiotherapy at different periods. Although radiotherapy can enhance the local …

Patient Derived Ex-Vivo Cancer Models in Drug Development, Personalized Medicine, and Radiotherapy

R Zitter, RM Chugh, S Saha - Cancers, 2022 - mdpi.com
Simple Summary This review article highlights gaps in the current system of drug
development and personalized medicine for cancer therapy. The ex vivo model system …

The Chromosome Passenger Complex (CPC) Components and Its Associated Pathways Are Promising Candidates to Differentiate Between Normosensitive and …

A Dietz, P Subedi, O Azimzadeh… - Biomarker …, 2024 - journals.sagepub.com
Background: Sensitivity to ionizing radiation differs between individuals, but there is a limited
understanding of the biological mechanisms that account for these variations. One example …

Cognitive and neuroimaging outcomes in individuals with benign and low-grade brain tumours receiving radiotherapy: A protocol for a prospective cohort study

SJ Hardy, AJ Finkelstein, M Tivarus, E Culakova… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Radiation-induced cognitive decline (RICD) occurs in 50%–90% of adult
patients 6 months post-treatment. In patients with low-grade and benign tumours with long …

Association of Radiation Dose to the Amygdala–Orbitofrontal Network with Emotion Recognition Task Performance in Patients with Low-Grade and Benign Brain …

SJ Hardy, A Finkelstein, MT Milano, G Schifitto, H Sun… - Cancers, 2023 - mdpi.com
Simple Summary Patients with brain tumors often experience changes in memory and other
aspects of thinking. Many may also have difficulty with social cognition, affecting the abilities …

[HTML][HTML] Review of the pathogenesis, diagnosis, and management of osteoradionecrosis of the femoral head

Y Li, Z Zhou, S Xu, J Jiang, J Xiao - Medical Science Monitor …, 2023 - ncbi.nlm.nih.gov
Osteoradionecrosis (ORN) of the femoral head is an important issue for orthopedists and
radiologists in clinical practice. With the rapid development of technological advances in …

[HTML][HTML] Adverse effects of chemoradiotherapy on invasion and metastasis of tumor cells

W Xiong, Y Liao, JY Qin, WH Li, ZY Tang - Genes & Diseases, 2020 - Elsevier
The phenomenon of enhanced invasion and metastasis of residual tumor cells has been
observed in an increasing number of patients receiving chemoradiotherapy recently, and …