Water is critical for survival and thirst is a powerful way of ensuring that fluid levels remain in
balance. Overconsumption, however, can have deleterious effects, therefore optimization …

Life of terrestrial vertebrates depends on the maintenance of water and salt in the
extracellular compartment (“internal milieu”) within strictly regulated boundaries …

Estradiol (E2) inhibits fluid intake in several species, which may help to defend fluid
homeostasis by preventing excessive extracellular fluid volume. Although this phenomenon …

Estradiol (E2) decreases both water and saline intakes by female rats. The ERα and ERβ
subtypes are expressed in areas of the brain that control fluid intake; however, the role that …

Previous in vivo and in vitro studies demonstrate that the angiotensin type 1 receptor rapidly
desensitizes after exposure to angiotensin II (AngII). Behaviorally, this likely underlies the …

The imidazoline I 2 receptor is an emerging drug target for analgesics. This study extended
previous studies by examining the antinociceptive effects of three I 2 receptor agonists (2 …

Angiotensin II (AngII) is a key component in the maintenance of body fluid homeostasis. It
has potent dipsetic* and natriorexigenic effects when injected into the brain of rats. This …

A single central injection of angiotensin II (AngII) potently increases water intake; however, a
growing body of research suggests that repeated, acute intracerebroventricular injections of …

Angiotensin II (Ang II) acts on central angiotensin type 1 (AT1) receptors to increase water
and saline intake. Prolonged exposure to Ang II in cell culture models results in a …

Abstract Angiotensin II (Ang II) stimulates water and saline intakes when injected into the
brain of rats. This arises from activation of the AT 1 Ang II receptor subtype. Acute repeated …