Chloroquine and sulfadoxine–pyrimethamine resistance in Sub-Saharan Africa—A review

AT Roux, L Maharaj, O Oyegoke, OP Akoniyon… - Frontiers in …, 2021 - frontiersin.org
Malaria is a great concern for global health and accounts for a large amount of morbidity and
mortality, particularly in Africa, with sub-Saharan Africa carrying the greatest burden of the …

Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Mali: a systematic review and meta-analysis

FO Maiga, M Wele, SM Toure, M Keita, CO Tangara… - Malaria Journal, 2021 - Springer
Background Artemisinin-based combination therapy (ACT) was deployed in 2005 as an
alternative to chloroquine and is considered the most efficacious treatment currently …

Haemoglobin changes and risk of anaemia following treatment for uncomplicated falciparum malaria in sub-Saharan Africa

J Zwang, U D'Alessandro, JL Ndiaye, AA Djimdé… - BMC infectious …, 2017 - Springer
Background Anaemia is common in malaria. It is important to quantitate the risk of anaemia
and to distinguish factors related to the natural history of disease from potential drug toxicity …

Comparison of anti-malarial drug efficacy in the treatment of uncomplicated malaria in African children and adults using network meta-analysis

S Whegang Youdom, R Tahar, LK Basco - Malaria Journal, 2017 - Springer
Background Artemisinin-based combination therapy (ACT) and novel drug combinations are
available and used in African countries to treat uncomplicated malaria. Network meta …

[HTML][HTML] Comparison of anti-malarial drug efficacy in the treatment of uncomplicated malaria in African children and adults using network meta-analysis

SW Youdom, R Tahar, LK Basco - Malaria Journal, 2017 - ncbi.nlm.nih.gov
Background Artemisinin-based combination therapy (ACT) and novel drug combinations are
available and used in African countries to treat uncomplicated malaria. Network meta …

Intramolecular Diaza‐Diels–Alder Protocol: A New Diastereoselective and Modular One‐Step Synthesis of Constrained Polycyclic Frameworks

V Srinivasulu, A Reddy, R Mazitschek… - … A European Journal, 2017 - Wiley Online Library
Phenotype‐based screening of diverse compound collections generated by privileged
substructure‐based diversity‐oriented synthesis (pDOS) is considered one of the prominent …

Nicotinamide inhibits the growth of P. falciparum and enhances the antimalarial effect of artemisinin, chloroquine and pyrimethamine

SO Tcherniuk, O Chesnokova, IV Oleinikov… - Molecular and …, 2017 - Elsevier
Abstract Nicotinamide (vitamin B3)–is a water soluble amide derivative of nicotinic acid,
which has been used at high doses for a variety of therapeutic applications. However, its …

Impact of three-year intermittent preventive treatment using artemisinin-based combination therapies on malaria morbidity in Malian schoolchildren

H Maiga, B Barger, I Sagara, A Guindo… - Tropical Medicine and …, 2020 - mdpi.com
Previous studies have shown that a single season of intermittent preventive treatment in
schoolchildren (IPTsc) targeting the transmission season has reduced the rates of clinical …

In Vivo Efficacy of Artesunate/Sulphadoxine-Pyrimethamine versus Artesunate/Amodiaquine in the Treatment of Uncomplicated P. falciparium Malaria in Children …

TO Apinjoh, JK Anchang-Kimbi, MU Ajonina… - Biomedicines, 2016 - mdpi.com
Background: The development and spread of antimalarial drug resistant parasites
contributes to the global impact of the disease. In vivo efficacy assessments of treatments for …

[HTML][HTML] Comparison of Efficacy and Safety of Artemisinin-Based Combination Therapies for Treating Uncomplicated Falciparum Malaria in Sub-Saharan African …

SW Youdom, RS Tchouenkou… - Advances in Infectious …, 2022 - scirp.org
Background: Several artemisinin-based combination therapies (ACT) are available to treat
uncomplicated malaria in Africa. The present study aimed to assess the ranking of their …