The C‐type lectin‐like domain superfamily

AN Zelensky, JE Gready - The FEBS journal, 2005 - Wiley Online Library
The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group
of extracellular Metazoan proteins with diverse functions. The CTLD structure has a …

Chronic fatigue syndrome, the immune system and viral infection

AS Bansal, AS Bradley, KN Bishop… - Brain, behavior, and …, 2012 - Elsevier
The chronic fatigue syndrome (CFS), as defined by recent criteria, is a heterogeneous
disorder with a common set of symptoms that often either follows a viral infection or a period …

[HTML][HTML] CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4

AJ Bankovich, LR Shiow, JG Cyster - Journal of Biological Chemistry, 2010 - ASBMB
Lymphocyte egress from lymph nodes requires the G-protein-coupled sphingosine 1-
phosphate receptor-1 (S1P 1). The activation antigen CD69 associates with and inhibits the …

[HTML][HTML] Characterization of the human β-glucan receptor and its alternatively spliced isoforms

JA Willment, S Gordon, GD Brown - Journal of Biological Chemistry, 2001 - ASBMB
β-1, 3-d-Glucans are biological response modifiers with potent effects on the immune
system. A number of receptors are thought to play a role in mediating these responses …

[HTML][HTML] A drug-sensitive genetic network masks fungi from the immune system

RT Wheeler, GR Fink - PLoS pathogens, 2006 - journals.plos.org
Fungal pathogens can be recognized by the immune system via their β-glucan, a potent
proinflammatory molecule that is present at high levels but is predominantly buried beneath …

Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination

K Natarajan, N Dimasi, J Wang… - Annual review of …, 2002 - annualreviews.org
In contrast to T cell receptors, signal transducing cell surface membrane molecules involved
in the regulation of responses by cells of the innate immune system employ structures that …

The cellular and molecular basis of CD69 function in anti-tumor immunity

R Koyama-Nasu, Y Wang, I Hasegawa… - International …, 2022 - academic.oup.com
Cancer immunotherapy utilizes our immune system to attack cancer cells and is an
extremely promising strategy for cancer treatment. Although immune-checkpoint blockade …

[HTML][HTML] Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor 1 ligand binding domain and its ligand recognition mode to OxLDL

I Ohki, T Ishigaki, T Oyama, S Matsunaga, Q Xie… - Structure, 2005 - cell.com
Lectin-like, oxidized low-density lipoprotein (LDL) receptor 1, LOX-1, is the major receptor
for oxidized LDL (OxLDL) in endothelial cells. We have determined the crystal structure of …

[HTML][HTML] Modulation of NK cell function by genetically coupled C-type lectin-like receptor/ligand pairs encoded in the human natural killer gene complex

Y Bartel, B Bauer, A Steinle - Frontiers in immunology, 2013 - frontiersin.org
Functional responses of natural killer (NK) cells including eradication of “harmful” cells and
modulation of immune responses are regulated by a broad variety of activating and …

Crucial role for CD 69 in allergic inflammatory responses: CD 69‐Myl9 system in the pathogenesis of airway inflammation

MY Kimura, K Hayashizaki, K Tokoyoda… - Immunological …, 2017 - Wiley Online Library
CD 69 has been known as an early activation marker of lymphocytes; whereas, recent
studies demonstrate that CD 69 also has critical functions in immune responses. Early …