Obesity and cancer risk: Emerging biological mechanisms and perspectives

KI Avgerinos, N Spyrou, CS Mantzoros, M Dalamaga - Metabolism, 2019 - Elsevier
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …

From leptin to other adipokines in health and disease: facts and expectations at the beginning of the 21st century

M Blüher, CS Mantzoros - Metabolism, 2015 - Elsevier
This year marks the 20th anniversary of the discovery of leptin, which has tremendously
stimulated translational obesity research. The discovery of leptin has led to realizations that …

The role of adiponectin in cancer: a review of current evidence

M Dalamaga, KN Diakopoulos… - Endocrine …, 2012 - academic.oup.com
Improving physical function and mobility in a continuously expanding elderly population
emerges as a high priority of medicine today. Muscle mass, strength/power, and maximal …

[HTML][HTML] Adiponectin, driver or passenger on the road to insulin sensitivity?

R Ye, PE Scherer - Molecular metabolism, 2013 - Elsevier
Almost 20 years have passed since the first laboratory evidence emerged that an abundant
message encoding a protein with homology to the C1q superfamily is highly specifically …

Leptin's role in lipodystrophic and nonlipodystrophic insulin-resistant and diabetic individuals

HS Moon, M Dalamaga, SY Kim, SA Polyzos… - Endocrine …, 2013 - academic.oup.com
Leptin is an adipocyte-secreted hormone that has been proposed to regulate energy
homeostasis as well as metabolic, reproductive, neuroendocrine, and immune functions. In …

Laboratory findings and biomarkers in Long COVID: what do we know so far? Insights into epidemiology, pathogenesis, therapeutic perspectives and challenges

D Tsilingiris, NG Vallianou, I Karampela… - International Journal of …, 2023 - mdpi.com
Long COVID (LC) encompasses a constellation of long-term symptoms experienced by at
least 10% of people after the initial SARS-CoV-2 infection, and so far it has affected about 65 …

Deciphering the association between psoriasis and obesity: current evidence and treatment considerations

K Paroutoglou, E Papadavid, GS Christodoulatos… - Current obesity …, 2020 - Springer
Abstract Purpose of Review Obesity and psoriasis represent chronic inflammatory states that
are interconnected in a vicious cycle, sharing also a degree of synergy. In this review, we …

[HTML][HTML] Of mice and men: Considerations on adipose tissue physiology in animal models of obesity and human studies

IG Lempesis, D Tsilingiris, J Liu, M Dalamaga - Metabolism open, 2022 - Elsevier
The ever-increasing burden of obesity demands a better pathophysiological understanding,
especially regarding adipose tissue pathophysiology. Animal models of obesity are of great …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Obesity and leukemia: biological mechanisms, perspectives, and challenges

D Tsilingiris, NG Vallianou, N Spyrou… - Current Obesity …, 2024 - Springer
Abstract Purpose of Review To examine the epidemiological data on obesity and leukemia;
evaluate the effect of obesity on leukemia outcomes in childhood acute lymphoblastic …