Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Strategies to counteract or prevent emerging drug resistance are crucial for the design of
next-generation antimalarials. In the past, resistant parasites were generally identified …

Abstract Background Partial resistance of Plasmodium falciparum to the artemisinin
component of artemisinin-based combination therapies, the most important malaria drugs …

In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …

Host genetic factors can confer resistance against malaria, raising the question of whether
this has led to evolutionary adaptation of parasite populations. Here we searched for …

Abstract We describe the MalariaGEN Pf7 data resource, the seventh release of
Plasmodium falciparum genome variation data from the MalariaGEN network. It comprises …

Background Malaria outbreaks are important public health concerns that can cause
resurgence in endemic regions approaching elimination. We investigated a Plasmodium …

Background CRISPR-based diagnostics are a new class of highly sensitive and specific
assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific …

Background: National Malaria Control Programmes (NMCPs) currently make limited use of
parasite genetic data. We have developed GenRe-Mekong, a platform for genetic …

Mosquito control remains a central pillar of efforts to reduce malaria burden in sub-Saharan
Africa. However, insecticide resistance is entrenched in malaria vector populations, and …