IL-10 is a multifunctional cytokine with both immunosuppressive and antiangiogenic
functions and may have both tumor-promoting and-inhibiting properties. A large number of …

BACKGROUND Genetic susceptibility studies of lymphoma may serve to identify at risk
populations and to elucidate important disease mechanisms. METHODS This review …

It is now widely accepted that elements of the cellular and tissue microenvironment are
crucial regulators of cell behavior inculture and homeostasis in vivo, and that many of the …

Background & Aims: Increasing evidence points toward a role of hepatitis C virus (HCV)
infection in the etiology of malignant lymphomas. However, previous epidemiologic studies …

Interactions between environment and immune system play an essential role in the
aetiology of immunopathologies, including lymphomas. Toll-like receptors (TLR) belong to a …

Neoplastic growth was often regarded as an autonomous process driven by uncontrolled
expansion of malignant cell population. This view is now being transformed as it becomes …

Background and Objective: Interleukin‐10 has been described as an anti‐inflammatory
cytokine and a B‐cell proliferation factor. Promoter polymorphisms of the interleukin‐10 …

Abstract Interleukin-10 (IL-10) is a multifunctional cytokine with both immunosuppressive
and anti-angiogenic functions and may have both tumour-promoting and-inhibiting …

Background Systemic inflammatory parameters are associated with poor outcomes in
malignant patients. Several inflammation-based cumulative prognostic score systems were …

The host immune system status remains an unresolved mystery among several
malignancies. An immune-compromised state or smart immune-surveillance tactics …