Depression is a prevalent disease worldwide, limiting psychosocial functioning and
thequality of life. Linalool is the main constituent of some essential oils from aromatic plants …

ABSTRACT Introduction: Basil (Ocimum basilicum L., OB) is a plant world widely used as a
spice and a typical ingredient of the healthy Mediterranean diet. In traditional medicine, OB …

Background The chronic unpredictable mild stress (CUMS) model has long been
considered the best model for exploring the pathophysiological mechanisms underlying …

Hesperidin, a kind of citrus bioflavonoid distributed in foods including grapefruits, oranges
and lemons, has many pharmacological activities. This study was aimed to evaluate the anti …

Chronic mild stress (CMS) model is most similar to the depression human suffered in daily
life. Strong evidence proved the important role of hippocampal synaptic plasticity in the …

Many vegetable extracts, essential oils, and their main constituents are active on the Central
Nervous System (CNS). In fact, they have been used as sedatives, hypnotics, or tranquilizers …

Rationale Selective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for
anxiety-like disorders. However, which aspects of anxiety are affected by SSRIs is not yet …

Depression is a mental disorder that affects more than 300 million people worldwide. The
medications available for treatment take a long time to exhibit therapeutic results and …

Background Cisplatin is a wide-ranging antineoplastic drug. Neurotoxicity is one of
cisplatin's side effects that restrict its usage. This study aimed to investigate the possible …

The etiopathogenesis of depression may involve repeated exposure to several
unpredictable stressors. This study was conducted to investigate changes induced by …