Role of thymic stromal lymphopoietin in allergy and beyond

R Ebina-Shibuya, WJ Leonard - Nature Reviews Immunology, 2023 - nature.com
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Regulation of immune responses by the airway epithelial cell landscape

RJ Hewitt, CM Lloyd - Nature Reviews Immunology, 2021 - nature.com
The community of cells lining our airways plays a collaborative role in the preservation of
immune homeostasis in the lung and provides protection from the pathogens and pollutants …

Somatosensory and autonomic neuronal regulation of the immune response

S Udit, K Blake, IM Chiu - Nature Reviews Neuroscience, 2022 - nature.com
Bidirectional communication between the peripheral nervous system (PNS) and the immune
system is a crucial part of an effective but balanced mammalian response to invading …

Gut-innervating nociceptors regulate the intestinal microbiota to promote tissue protection

W Zhang, M Lyu, NJ Bessman, Z Xie, M Arifuzzaman… - Cell, 2022 - cell.com
Nociceptive pain is a hallmark of many chronic inflammatory conditions including
inflammatory bowel diseases (IBDs); however, whether pain-sensing neurons influence …

Heterogeneity of type 2 innate lymphoid cells

H Spits, J Mjösberg - Nature Reviews Immunology, 2022 - nature.com
More than a decade ago, type 2 innate lymphoid cells (ILC2s) were discovered to be
members of a family of innate immune cells consisting of five subsets that form a first line of …

A chemogenetic screen reveals that Trpv1-expressing neurons control regulatory T cells in the gut

Y Zhu, KA Meerschaert, S Galvan-Pena, NR Bin… - Science, 2024 - science.org
Neuroimmune cross-talk participates in intestinal tissue homeostasis and host defense.
However, the matrix of interactions between arrays of molecularly defined neuron subsets …

Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces

AM Tsou, H Yano, CN Parkhurst, T Mahlakõiv, C Chu… - Nature, 2022 - nature.com
Emerging studies indicate that cooperation between neurons and immune cells regulates
antimicrobial immunity, inflammation and tissue homeostasis. For example, a neuronal …

Neuroimmune interactions in the intestine

A Wallrapp, IM Chiu - Annual Review of Immunology, 2024 - annualreviews.org
Recent advances have contributed to a mechanistic understanding of neuroimmune
interactions in the intestine and revealed an essential role of this cross talk for gut …

Nonresolving inflammation redux

C Nathan - Immunity, 2022 - cell.com
Nonresolving inflammation contributes to many diseases, including COVID-19 in its fatal and
long forms. Our understanding of inflammation is rapidly evolving. Like the immune system …

The cancer-immune dialogue in the context of stress

Y Ma, G Kroemer - Nature Reviews Immunology, 2024 - nature.com
Although there is little direct evidence supporting that stress affects cancer incidence, it does
influence the evolution, dissemination and therapeutic outcomes of neoplasia, as shown in …