Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has
a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both …

In 2021 the World Health Organization published the fifth and latest version of the Central
Nervous System tumors classification, which incorporates and summarizes a long list of …

Despite a generally better prognosis than high-grade glioma (HGG), recurrence and
malignant progression are the main causes for the poor prognosis and difficulties in the …

BACKGROUND Liver cancer has a high mortality and morbidity rate throughout the world. In
clinical practice, the prognosis of liver cancer patients is poor, and the complex reasons …

Glioma, a kind of central nervous system (CNS) tumor, is hard to cure and accounts for 32%
of all CNS tumors. Establishing a stable glioma model is critically important to investigate the …

Simple Summary Glioblastoma (GBM) is one of the most aggressive tumor types with no
effective treatment options. To create new routes for therapy, it is necessary to continue …

The retinoblastoma gene (RB1) is a tumor suppressor gene that serves a key role in the
development of numerous tumor diseases that can be downregulated by DNA methylation …

Glioblastoma multiforme (GBM) is one of the most common and malignant form of adult brain
tumor with a high mortality rate and dismal prognosis. The present standard treatment …

Glioblastoma (GBM) is the most malignant glioma with an extremely poor prognosis. It is
characterized by high vascularization and its growth depends on the formation of new blood …

Background: Pisosterol, a triterpene derived from Pisolithus tinctorius, exhibits potential
antitumor activity in various malignancies. However, the molecular mechanisms that mediate …