[HTML][HTML] CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens

J Thomas, A Klebanov, S John, LS Miller… - Genes & …, 2023 - ncbi.nlm.nih.gov
The CEA family comprises 18 genes and 11 pseudogenes located at chromosome 19q13. 2
and is divided into two main groups: cell surface anchored CEA-related cell adhesion …

Gastric cancer in patients with gastric atrophy and intestinal metaplasia: A systematic review and meta-analysis

M Akbari, R Tabrizi, S Kardeh, KB Lankarani - PloS one, 2019 - journals.plos.org
Aim Intestinal metaplasia (IM) and gastric atrophy (GA) are precancerous lesions in the
stomach. There is a large debate on natural course of these lesions and surveillance …

Dual-inhibitory domain iCARs improve the efficiency of the AND-NOT gate CAR T strategy

NJ Bangayan, L Wang, G Burton Sojo… - Proceedings of the …, 2023 - National Acad Sciences
CAR (chimeric antigen receptor) T cell therapy has shown clinical success in treating
hematological malignancies, but its treatment of solid tumors has been limited. One major …

[HTML][HTML] Apposition of fibroblasts with metaplastic gastric cells promotes dysplastic transition

SH Lee, EWC Panta, D Gibbs, Y Won, J Min, C Zhang… - Gastroenterology, 2023 - Elsevier
Background & Aims Elements of field cancerization, including atrophic gastritis, metaplasia,
and dysplasia, promote gastric cancer development in association with chronic …

Intracellular delivery of therapeutic antibodies into specific cells using antibody-peptide fusions

J Gaston, N Maestrali, G Lalle, M Gagnaire… - Scientific reports, 2019 - nature.com
Because of their favorable properties as macromolecular drugs, antibodies are a very
successful therapeutic modality for interfering with disease-relevant targets in the …

CEACAM5 stimulates the progression of non-small-cell lung cancer by promoting cell proliferation and migration

X Zhang, X Han, P Zuo, X Zhang… - Journal of International …, 2020 - journals.sagepub.com
Objective To detect the expression of CEA-related cell adhesion molecule 5 (CEACAM5) in
non-small-cell lung cancer (NSCLC) and explore its function in the progression and …

Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth

M Böckers, NW Paul, T Efferth - Toxicology and applied pharmacology, 2020 - Elsevier
Plastic in the ocean degrades to microplastic, thereby enhancing the leaching of
incorporated plasticizers due to the increased particle surface. The uptake of microplastic …

Oncogenic transcription factors instruct promoter-enhancer hubs in individual triple negative breast cancer cells

J Zhao, Y Zhou, I Tzelepis, NG Burget, J Shi… - Science …, 2024 - science.org
Sequencing-based mapping of ensemble pairwise interactions among regulatory elements
support the existence of topological assemblies known as promoter-enhancer hubs or …

Sequencing and Bioinformatics analysis of lncRNA/circRNA-miRNA-mRNA in Glioblastoma multiforme

R Wang, Q Li, X Chu, N Li, H Liang, F He - Metabolic Brain Disease, 2023 - Springer
Evidence suggests that non-coding RNAs have a role in glioblastoma multiforme (GBM),
although the regulatory mechanisms controlled by competing endogenous RNAs (ceRNAs) …

An optical microfiber biosensor for CEACAM5 detection in serum: Sensitization by a nanosphere interface

A Xiao, Y Huang, J Zheng, P Chen… - ACS applied materials & …, 2019 - ACS Publications
The detection of carcinoembryonic antigen (CEA)-related cell adhesion molecules 5
(CEACAM5) is significant in cancer prewarning. Early diagnosis can effectively alleviate the …