Amyloid polymorphism in the protein folding and aggregation energy landscape

J Adamcik, R Mezzenga - Angewandte Chemie International …, 2018 - Wiley Online Library
Protein folding involves a large number of steps and conformations in which the folding
protein samples different thermodynamic states characterized by local minima. Kinetically …

Conversion of light into macroscopic helical motion

S Iamsaard, SJ Aßhoff, B Matt, T Kudernac… - Nature …, 2014 - nature.com
A key goal of nanotechnology is the development of artificial machines capable of
converting molecular movement into macroscopic work. Although conversion of light into …

Helical structures mimicking chiral seedpod opening and tendril coiling

G Wan, C Jin, I Trase, S Zhao, Z Chen - Sensors, 2018 - mdpi.com
Helical structures are ubiquitous in natural and engineered systems across multiple length
scales. Examples include DNA molecules, plants' tendrils, sea snails' shells, and spiral …

Programmed morphing of liquid crystal networks

LT de Haan, APHJ Schenning, DJ Broer - Polymer, 2014 - Elsevier
A promising candidate for the development of stimuli-responsive morphing materials are
based on liquid crystal polymer networks. These anisotropic materials will contract along the …

Competition between crystal and fibril formation in molecular mutations of amyloidogenic peptides

NP Reynolds, J Adamcik, JT Berryman… - Nature …, 2017 - nature.com
Amyloidogenic model peptides are invaluable for investigating assembly mechanisms in
disease related amyloids and in protein folding. During aggregation, such peptides can …

Polymorphism complexity and handedness inversion in serum albumin amyloid fibrils

I Usov, J Adamcik, R Mezzenga - ACS nano, 2013 - ACS Publications
Protein-based amyloid fibrils can show a great variety of polymorphic structures within the
same protein precursor, although the origins of these structural homologues remain poorly …

Preparation of biomimetic photoresponsive polymer springs

S Iamsaard, E Villemin, F Lancia, SJ Aβhoff… - Nature protocols, 2016 - nature.com
Polymer springs that twist under irradiation with light, in a manner that mimics how plant
tendrils twist and turn under the effect of differential expansion in different sections of the …

Towards lysozyme nanotube and 3D hybrid self-assembly

C Lara, S Handschin, R Mezzenga - Nanoscale, 2013 - pubs.rsc.org
We report lysozyme self-assembly into nanotubes, under the effect of hydrolysis at pH 2 and
90° C. We resolve the final steps of the fibrillation pathway, entailing the closure of multi …

Highly tunable actuation and mechanical properties of 4D-printed nematic liquid crystal elastomers

Z Siddiqui, J Smay, A Azoug - Mechanics of Materials, 2022 - Elsevier
Liquid crystal elastomers (LCEs) are smart elastomers capable of a reversible shape
change triggered by a stimulus such as heat or light. This change in shape is programmed …

Shape and chirality transitions in off-axis twist nematic elastomer ribbons

Y Sawa, K Urayama, T Takigawa, V Gimenez-Pinto… - Physical Review E …, 2013 - APS
Using both experiments and finite element simulations, we explore the shape evolution of off-
axis twist nematic elastomer ribbons as a function of temperature. The elastomers are …