Background Mitochondrial oxidative function plays a key role in the development of non-
alcoholic fatty liver disease (NAFLD) and insulin resistance (IR). Recent studies reported …

For long time bilirubin was only considered as a potentially dangerous sign of liver diseases,
but it now appears clear that it is also a powerful signaling molecule. Together with potent …

The measurement of physicochemical parameters in living cells can provide information on
individual cellular organelles, helping us to understand subcellular function in health and …

Bilirubin is one of the most frequently measured metabolites in medicine, yet its physiologic
roles remain unclear. Bilirubin can act as an antioxidant in vitro, but whether its redox activity …

Optical fluorescence microscopy plays a pivotal role in the exploration of biological structure
and dynamics, especially on live specimens. Progress in the field relies, on the one hand, on …

Although the role of hydrophilic antioxidants in the development of hepatic insulin resistance
and nonalcoholic fatty liver disease has been well studied, the role of lipophilic antioxidants …

Dopamine is a well-known neurotransmitter due to its involvement in Parkinson's disease
(PD). Dopamine is not only involved in PD but also controls multiple mental and physical …

We introduce UnaG as a green-to-dark photoswitching fluorescent protein capable of high-
quality super-resolution imaging with photon numbers equivalent to the brightest …

Bilirubin is a yellow endogenous derivate of the heme catabolism. Since the 1980s, it has
been recognized as one of the most potent antioxidants in nature, able to counteract …

Among antioxidants in the human body, bilirubin has been recognized over the past 20
years to afford protection against different chronic conditions, including inflammation and …