As a dual-function protein, prosaposin (PSAP) is a lysosome-associated protein that
participates in a variety of cellular processes. In the lysosome, PSAP is processed to activate …

Background As a neurotrophic factor, prosaposin (PSAP) can exert neuroprotective and
neurotrophic effects. It is involved in the occurrence and development of prostate and breast …

HtrA1 appears to be involved in several physiological processes as well as in the
pathogenesis of conditions such as Alzheimer's disease and osteoarthritis. It has also been …

Mesenchymal glioblastoma (GBM) is the most aggressive subtype of GBM. Our previous
study found that neurotrophic factor prosaposin (PSAP) is highly expressed and secreted in …

Background: Malignant pleural mesothelioma (MPM) a rare neoplasm linked to asbestos
exposure is characterized by a poor prognosis. Soluble mesothelin is currently considered …

Background Poor prognosis in gallbladder cancer is due to late presentation of the disease,
lack of reliable biomarkers for early diagnosis and limited targeted therapies. Early …

Promoter methylation in various tumor suppressor genes is reported to influence gallbladder
carcinogenesis. Here, we aimed to identify methylation status in gallbladder cancer (GBC) …

Hepatocellular carcinoma (HCC) is the most common malignancy in liver and is one of the
leading causes of cancer-induced deaths all over the world. Circular RNAs (circRNAs) have …

Background Transgelin is supposed to be a tumor suppression gene and it is down-
regulated in a variety of human cancers. However, the role of transgelin in different cancers …

Urinary biomarkers can diagnose and monitor pathophysiologic conditions in the central
nervous system (CNS). However, focus is often on single diseases, with limited data on …