The proliferation and global expansion of multidrug-resistant (MDR) bacteria have
deepened the need to develop novel antimicrobials. Antimicrobial peptides (AMPs) are …

This article provides an overview of the development, structure and activity of various metal
complexes with anti-cancer activity. Chemical researchers continue to work on the …

Developing new antimicrobials as alternatives to conventional antibiotics has become an
urgent race to eradicate drug-resistant bacteria and to save human lives. Conventionally …

Fish, like all other animals, are exposed to constant contact with microbes, both on their skin
and on the surfaces of their respiratory and digestive systems. Fish have a system of non …

Outbreaks of viral diseases are on the rise, fueling the search for antiviral therapeutics that
act on a broad range of viruses while remaining safe to human host cells. In this research …

In the search for novel broad-spectrum therapeutics to fight chronic infections, inflammation,
and cancer, host defense peptides (HDPs) have garnered increasing interest …

Transition metal ions such as iron, copper, zinc, manganese or, nickel are essential in many
biological processes. Bacteria have developed a number of mechanisms for their acquisition …

The spore-forming intestinal pathogen Clostridioides difficile causes multidrug resistant
infection with a high rate of recurrence after treatment. Piscidins 1 (p1) and 3 (p3), cationic …

Antimicrobial resistance has significantly increased over the last 30 years, prompting
scientists to continuously look for novel, effective ways to combat drug-resistant bacteria and …

Many microbes produce siderophores, which are extremely potent weapons capable of
stealing iron ions from human tissues, fluids and cells and transferring them into bacteria …