It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

Aims We aimed to investigate the distribution of exercise capacity across the spectrum of
adult congenital heart disease (ACHD) using own data and the published experience and to …

Background: Multicenter longitudinal objective data for survival into adulthood of patients
who have undergone Fontan procedures are lacking. Objectives: This study sought to …

All children have a natural need to move, play, and perform activities. Physical activity is
necessary for optimal physical, emotional, and psychosocial development for healthy …

Congenital heart disease (CHD) is the most common form of serious birth defect, occurring
in 8 per 1000 live births. 1 The past several decades have seen dramatic improvements in …

Objective: To develop clinical predictive nomograms generating per-patient numerical
probabilities of postoperative recurrence-free and overall survival at specific times …

A normal mammalian cardiovascular system consists of a double circuit, pulmonary and
systemic, connected in series and powered by a double pump. In the absence of congenital …

Aims Liver fibrosis and cirrhosis are a consequence of a Fontan physiology, and determine
prognosis. It is unclear whether non-invasive assessment of liver pathology is helpful to …

Background: Atrioventricular valve failure (moderate or greater regurgitation, or valve
operation) is a risk factor for adverse outcomes in patients undergoing Fontan palliation …

Background Despite an ageing Fontan population, data on late outcomes are still scarce.
Reported outcome measures and determinants vary greatly between studies making …