A review and update of mechanisms of estrogen in the hippocampus and amygdala for anxiety and depression behavior

AA Walf, CA Frye - Neuropsychopharmacology, 2006 - nature.com
Estrogen (E 2) has many effects in the central nervous system, including effects on anxiety
and depression behavior. This review will address effects of E 2 on behaviors related to …

Sex differences in psychopathology: of gonads, adrenals and mental illness

MB Solomon, JP Herman - Physiology & behavior, 2009 - Elsevier
Stress-related disorders such as anxiety and depression are disproportionately prevalent in
women. Women are more likely to experience depression and anxiety disorders during …

Menstrual cycle phase modulates reward-related neural function in women

JC Dreher, PJ Schmidt, P Kohn… - Proceedings of the …, 2007 - National Acad Sciences
There is considerable evidence from animal studies that the mesolimbic and mesocortical
dopamine systems are sensitive to circulating gonadal steroid hormones. Less is known …

Detailed analysis of the behavior of Lister and Wistar rats in anxiety, object recognition and object location tasks

A Ennaceur, S Michalikova, A Bradford… - Behavioural brain …, 2005 - Elsevier
The present study, examines some issues in the measure and analysis of behavior in
animals. Two strains of rats of both genders were used to illustrate and discuss these issues …

Estrogen and/or progesterone administered systemically or to the amygdala can have anxiety-, fear-, and pain-reducing effects in ovariectomized rats.

CA Frye, AA Walf - Behavioral neuroscience, 2004 - psycnet.apa.org
Estrogen (E₂) and/or progesterone (P) in the amygdala may influence anxiety, fear, and
pain behaviors. Ovariectomized rats were administered subcutaneous or intra-amygdala …

Male and female rats differ in brain cannabinoid CB1 receptor density and function and in behavioural traits predisposing to drug addiction: effect of ovarian hormones

M Paola Castelli, P Fadda, A Casu… - Current …, 2014 - ingentaconnect.com
Sex-dependent differences are frequently observed in the biological and behavioural effects
of substances of abuse, including cannabis. We recently demonstrated a modulating effect …

The effect of gonadal hormones and gender on anxiety and emotional learning

DJ Toufexis, KM Myers, M Davis - Hormones and behavior, 2006 - Elsevier
Disorders of anxiety and fear dysregulation are highly prevalent. These disorders affect
women approximately 2 times more than they affect men, occur predominately during a …

Differential effects of ovarian steroids on anxiety versus fear as measured by open field test and fear-potentiated startle

R Hiroi, JF Neumaier - Behavioural brain research, 2006 - Elsevier
The ovarian steroids, estrogen (E) and progesterone (P), have been shown to affect anxiety
and fear in humans and animals, although with inconsistent results. These ambiguous …

Anxiolytic effects of diazepam and ethanol in two behavioral models: comparison of males and females

MA Wilson, PR Burghardt, KA Ford… - Pharmacology …, 2004 - Elsevier
The present study compared the anxiolytic effects of the benzodiazepine agonist diazepam
and ethanol in adult male and female rats. Varying doses of diazepam (1–3 mg/kg) or …

Antianxiety and antidepressive behavior produced by physiological estradiol regimen may be modulated by hypothalamic–pituitary–adrenal axis activity

AA Walf, CA Frye - Neuropsychopharmacology, 2005 - nature.com
Variations in estradiol (E 2) may influence expression of stress-related anxiety and
depression symptoms among women. Effects of E 2 and stress on anxiety and depressive …