S Umemura, H Arima, S Arima, K Asayama… - Hypertension …, 2019 - nature.com
The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …
Importance Excess aldosterone production contributes to hypertension in both classical hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …
Autonomous aldosterone overproduction represents the underlying condition of 5–10% of patients with arterial hypertension and carries a significant burden of mortality and morbidity …
Besides the physiological regulation of water, sodium, and potassium homeostasis, aldosterone modulates several physiological and pathological processes in the …
Primary aldosteronism is a common cause of hypertension and is a risk factor for cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
Background: Primary aldosteronism is a common cause of treatment-resistant hypertension. However, evidence from local health systems suggests low rates of testing for primary …
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …
A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …
MC Zennaro, S Boulkroun… - Nature Reviews …, 2020 - nature.com
Early diagnosis and appropriate treatment of primary aldosteronism, the most frequent cause of secondary hypertension, are crucial to prevent deleterious cardiovascular …