Neuroimaging standards for research into small vessel disease—advances since 2013

M Duering, GJ Biessels, A Brodtmann, C Chen… - The Lancet …, 2023 - thelancet.com
Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

The potential impact of neuroimaging and translational research on the clinical management of lacunar stroke

S Rudilosso, A Rodríguez-Vázquez, X Urra… - International journal of …, 2022 - mdpi.com
Lacunar infarcts represent one of the most frequent subtypes of ischemic strokes and may
represent the first recognizable manifestation of a progressive disease of the small …

Cerebral small vessel disease: a review of the pathophysiological mechanisms

Y Hannawi - Translational Stroke Research, 2024 - Springer
Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

Cerebral vascular dysfunctions detected in human small vessel disease and implications for preclinical studies

JM Wardlaw, H Benveniste… - Annual Review of …, 2022 - annualreviews.org
Cerebral small vessel disease (SVD) is highly prevalent and a common cause of ischemic
and hemorrhagic stroke and dementia, yet the pathophysiology is poorly understood. Its …

[HTML][HTML] Vascular cognitive impairment–Past, present, and future challenges

A Badji, J Youwakim, A Cooper, E Westman… - Ageing Research …, 2023 - Elsevier
Vascular cognitive impairment (VCI) is a lifelong process encompassing a broad spectrum of
cognitive disorders, ranging from subtle or mild deficits to prodromal and fully developed …

Association of intensive vs standard blood pressure control with cerebral blood flow: secondary analysis of the SPRINT MIND randomized clinical trial

S Dolui, JA Detre, SA Gaussoin, JS Herrick… - JAMA …, 2022 - jamanetwork.com
Importance Antihypertensive treatments benefit cerebrovascular health and cognitive
function in patients with hypertension, but it is uncertain whether an intensive blood pressure …

Sex differences in cerebral small vessel disease: a systematic review and meta-analysis

L Jiménez-Sánchez, OKL Hamilton, U Clancy… - Frontiers in …, 2021 - frontiersin.org
Background: Cerebral small vessel disease (SVD) is a common cause of stroke, mild
cognitive impairment, dementia and physical impairments. Differences in SVD incidence or …

Retinal capillary microvessel morphology changes are associated with vascular damage and dysfunction in cerebral small vessel disease

SJ Wiseman, JF Zhang, C Gray… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cerebral small vessel disease (SVD) is a cause of stroke and dementia. Retinal capillary
microvessels revealed by optical coherence tomography angiography (OCTA) are …

Quantitative water permeability mapping of blood-brain-barrier dysfunction in aging

JN Ford, Q Zhang, EM Sweeney, AE Merkler… - Frontiers in Aging …, 2022 - frontiersin.org
Blood-brain-barrier (BBB) dysfunction is a hallmark of aging and aging-related disorders,
including cerebral small vessel disease and Alzheimer's disease. An emerging biomarker of …

Blood pressure variability and cerebral perfusion decline: a post hoc analysis of the SPRINT MIND trial

IJ Sible, DA Nation - Journal of the American Heart Association, 2023 - Am Heart Assoc
Background Blood pressure variability (BPV) is predictive of cerebrovascular disease and
dementia, possibly though cerebral hypoperfusion. Higher BPV is associated with cerebral …