Glycine is a major amino acid in mammals and other animals. It is synthesized from serine,
threonine, choline, and hydroxyproline via inter-organ metabolism involving primarily the …

It is only during the last decade that the functions of sinusoidal endothelial cells, Kupffer
cells, hepatic stellate cells, pit cells and other intrahepatic lymphocytes have been better …

L-Glycine: a novel antiinflammatory, immunomodulatory, and c... : Current Opinion in Clinical
Nutrition & Metabolic Care L-Glycine: a novel antiinflammatory, immunomodulatory, and …

The activation of nuclear factor-kappa B (NF-κB) in vascular endothelial cells may be
involved in vascular pathogeneses such as vasculitis or atherosclerosis. Recently, it has …

BACKGROUND/AIMS: Hepatic ischemia followed by reperfusion (I/R) is a major clinical
problem during transplantation, liver resection for tumor, and circulatory shock, producing …

In recent years, it has become appreciated that immune cells have different metabolic
profiles depending on their activation status. During sepsis, circulating leukocytes go …

Cholestasis is the stoppage of bile flow which could lead to serious clinical complications if
not managed. Cytotoxic bile acids are involved in the pathogenesis of liver injury during …

Background & Aims: In this study, the effect of dietary glycine on experimental colitis induced
by 2, 4, 6-trinitrobenzene sulphonic acid (TNBS) and dextran sulfate sodium (DSS) in the rat …

Recent studies have demonstrated that glycine blunts the response of Kupffer cells to
endotoxin. Based on pharmacological evidence, it was hypothesized that Kupffer cells and …

The study investigated the mechanism by which glycine protects against increased
circulating nonesterified fatty acids (NEFA), fat cell size, intra-abdominal fat accumulation …