As a result of recent advances, remarkable images revealing the distribution of complex
lipids in tissues are now generated by matrix-assisted laser desorption/ionization imaging …

The potential of matrix-assisted laser desorption ionization (MALDI) and MALDI-post-source
decay (PSD) time-of-flight mass spectrometry for the characterization of peptides and …

Matrix-assisted laser desorption/ionization (MALDI) coupled with ion mobility–mass
spectrometry (IM–MS) provides a rapid (μs–ms) means for the two-dimensional (2D) …

Increased efforts are being made to develop miniature mass spectrometers, including those
which are hand‐portable, and to retain the performance characteristics of traditional …

Direct tissue profiling and imaging mass spectrometry (MS) provide a molecular assessment
of numerous expressed proteins within a tissue sample. MALDI MS (matrix-assisted laser …

MALDI MS imaging mass spectrometry can be used to map the distribution of targeted
compounds in tissue sections with a spatial resolution currently of about 50 μm, providing …

An ion trap/ion mobility/time-of-flight mass spectrometry technique is shown to be a rapid
and sensitive means of analyzing peptide/protein mixtures. In this approach, an ion trap is …

Over the last 20 years, biological MS has changed out of all recognition. This is primarily due
to the development in the 1980s of 'soft ionization'methods that permit the ionization and …

As we enter the 21st century, the practice of mass spectrometry has been making ever
broadening contributions to our understanding of nature for slightly over 100 years. The …

Mass spectrometry can be used to map the distribution of targeted compounds in tissue,
providing important molecular information in many areas of biological research. Matrix …