The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Cell traction force plays a critical role in directing cellular functions, such as proliferation,
migration, and differentiation. Current understanding of cell traction force is largely derived …

Nature uses discrete molecular building blocks to form polymers that assemble into
multicomponent, multi-dynamic networks, inside (cytoskeleton) and outside (extracellular …

The fibrous network of an extracellular matrix (ECM) possesses mechanical properties that
convey critical biological functions in cell mechanotransduction. Engineered fibrous …

The engineering construction of the liver has attracted enormous attention. Organoids, as
emerging miniature three-dimensional cultivation units, hold significant potential in the …

The mechanical interaction between cells and the extracellular matrix (ECM) is fundamental
to coordinate collective cell behavior in tissues. Relating individual cell-level mechanics to …

The high reoperation rate in pelvic organ prolapse (POP) surgery is probably due to
impaired wound healing, and therefore, novel strategies that promote tissue regeneration …

Mechanical stimuli from the extracellular matrix (ECM) modulate vascular differentiation,
morphogenesis and dysfunction of the vasculature. With innovation in measurements, we …

Over the last decade, water-soluble polyisocyanopeptides (PICs) have emerged as a new
class of biomimetic polymers. Analogous to biopolymers, PICs exhibit a semi-flexible nature; …

Organoids have emerged as a powerful platform for studying complex biological processes
and diseases in vitro. However, most studies have focused on individual organoids …