Ultra‐high dose rate dosimetry: challenges and opportunities for FLASH radiation therapy

F Romano, C Bailat, PG Jorge, MLF Lerch… - Medical …, 2022 - Wiley Online Library
The clinical translation of FLASH radiotherapy (RT) requires challenges related to dosimetry
and beam monitoring of ultra‐high dose rate (UHDR) beams to be addressed. Detectors …

Radiochromic films for the two-dimensional dose distribution assessment

P Casolaro - Applied Sciences, 2021 - mdpi.com
Radiochromic films are mainly used for two-dimensional dose verification in photon,
electron, and proton therapy treatments. Moreover, the radiochromic film types available …

Feasibility of proton FLASH irradiation using a synchrocyclotron for preclinical studies

A Darafsheh, Y Hao, T Zwart, M Wagner… - Medical …, 2020 - Wiley Online Library
Purpose It has been recently shown that radiotherapy at ultrahigh dose rates (> 40 Gy/s,
FLASH) has a potential advantage in sparing healthy organs compared to that at …

Spread‐out Bragg peak proton FLASH irradiation using a clinical synchrocyclotron: proof of concept and ion chamber characterization

A Darafsheh, Y Hao, X Zhao, T Zwart… - Medical …, 2021 - Wiley Online Library
Purpose The purpose of this work is to (a) demonstrate the feasibility of delivering a spread‐
out Bragg peak (SOBP) proton beam in ultra‐high dose rate (FLASH) using a proton therapy …

Development of ultra-high dose-rate (FLASH) particle therapy

MM Kim, A Darafsheh, J Schuemann… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Research efforts in FLASH radiotherapy (FLASH-RT) have increased at an accelerated pace
recently. FLASH-RT involves ultra-high dose rates and has been shown to reduce toxicity to …

Response characterization of EBT‐XD radiochromic films in megavoltage photon and electron beams

EY León‐Marroquín, D Mulrow, A Darafsheh… - Medical …, 2019 - Wiley Online Library
Purpose The purpose of this study was to investigate the beam quality dependence of the
EBT‐XD radiochromic films for megavoltage photon and electron beam irradiations by …

Characterisation and Quenching Correction for an Al2O3:C Optical Fibre Real Time System in Therapeutic Proton, Helium, and Carbon-Charged Beams

L de Freitas Nascimento, P Leblans, B van der Heyden… - Sensors, 2022 - mdpi.com
Real time radioluminescence fibre-based detectors were investigated for application in
proton, helium, and carbon therapy dosimetry. The Al2O3: C probes are made of one single …

Characterization and quenching correction for a 2D real time radioluminescent system in therapeutic proton and carbon charged beams

LF Nascimento, P Leblans, B van der Heyden… - Sensors and Actuators A …, 2022 - Elsevier
Two dimensional radioluminescence (RL) films were investigated for application in proton
and carbon therapy dosimetry. The films are made of Al 2 O 3: C, Mg micro powder in two …

Radiochromic film dosimetry for protons up to 10 MeV with EBT2, EBT3 and unlaminated EBT3 films

D Sanchez-Parcerisa, I Sanz-García… - Physics in Medicine …, 2021 - iopscience.iop.org
Passive dosimetry with radiochromic films is widely used in proton radiotherapy, both in
clinical and scientific environments, thanks to its simplicity, high spatial resolution and dose …

Influence of 0.35 T magnetic field on the response of EBT3 and EBT‐XD radiochromic films

A Darafsheh, Y Hao, B Maraghechi, J Cammin… - Medical …, 2020 - Wiley Online Library
Purpose To investigate the inconsistency of recent literature on the effect of magnetic field
on the response of radiochromic films, we studied the influence of 0.35 T magnetic field on …