Effect of temperature and composition on solubility and thermodynamics of salicylic acid in aqueous mixtures of betaine-based deep eutectic solvents

P Jafari, M Barzegar-Jalali, A Jouyban - Korean Journal of Chemical …, 2023 - Springer
Solubility of salicylic acid in binary mixtures of water and betaine/propylene glycol (Bet/PG,
molar ratio of 1: 5), betaine/ethylene glycol (Bet/EG, molar ratio of 1: 3) or betaine/glycerol …

Enhancing the equilibrium solubility of salicylic acid in aqueous media by using polyethylene glycols 200, 400 and 600 as cosolvents: correlation and dissolution …

S Khezri, P Jafari, E Rahimpour, A Jouyban - The Journal of Chemical …, 2023 - Elsevier
The solubility of salicylic acid in three mixtures of polyethylene glycol (PEG) with different
molar masses of 200 to 600 g/mole were experimentally determined by a shake flask …

Solubility of Salicylic Acid in Some (Ethanol+ Water) Mixtures at Different Temperatures: Determination, Correlation, Thermodynamics and Preferential Solvation

S Akay, B Kayan, MÁ Peña, A Jouyban… - International Journal of …, 2023 - Springer
Equilibrium mole fraction solubility of salicylic acid in nine aqueous-ethanolic mixtures, as
well as in neat water and neat ethanol, was determined at seven temperatures from …

Solubility analysis of pharmaceuticals guaifenesin, ketoprofen, and artemisinin in different solvents

M Sadeghi, F Cascella, V Tenberg… - Journal of Molecular …, 2021 - Elsevier
Solubility is a fundamental parameter in the discovery of new drug molecules as well as in
their production using crystallization processes. In this work, we experimentally investigate …

Determination and Correlation of the Solubility of 1, 3-Cyclohexanedione Form I in Fourteen Pure Solvents at Temperatures from 288.15 to 333.15 K

B Zhang, Q Yin, Y Xiao, M Sun, L Zhou… - Journal of Chemical & …, 2023 - ACS Publications
The solubility of 1, 3-cyclohexanedione form I (CHD1) was determined using a gravimetric
method, spanning temperatures from 288.15 to 333.15 K across 14 solvents (acetonitrile …

New Screening Protocol for Effective Green Solvents Selection of Benzamide, Salicylamide and Ethenzamide

M Przybyłek, A Miernicka, M Nowak, P Cysewski - Molecules, 2022 - mdpi.com
New protocol for screening efficient and environmentally friendly solvents was proposed and
experimentally verified. The guidance for solvent selection comes from computed solubility …

Investigating the Influence of Processing Conditions on Dissolution and Physical Stability of Solid Dispersions with Fenofibrate and Mesoporous Silica

A Baumgartner, N Dobaj, O Planinšek - Pharmaceutics, 2024 - mdpi.com
The study aimed to enhance the solubility of the poorly water-soluble drug, fenofibrate, by
loading it onto mesoporous silica, forming amorphous solid dispersions. Solid dispersions …

[HTML][HTML] Predicting drug solubility in organic solvents mixtures: A machine-learning approach supported by high-throughput experimentation

F Cenci, S Diab, P Ferrini, C Harabajiu, M Barolo… - International Journal of …, 2024 - Elsevier
A novel approach based on supervised machine-learning is proposed to predict the
solubility of drugs and drug-like molecules in mixtures of organic solvents. Similar to …

Characterization, Solubility, and Hygroscopicity of BMS-817399

R Prasad, S Kocevska, D Skliar… - … Process Research & …, 2024 - ACS Publications
Characteristics of BMS-817399 that could influence the potential utility of the compound as
an active pharmaceutical ingredient (API) have been explored. The compound exists as a …

Solubility of 2-Hydroxybenzoic Acid in Pseudo-Binary Mixtures of Choline Chloride/Propylene Glycol Deep Eutectic Solvent+ Water at 293.15–313.15 K

E Babaei, P Jafari, E Rahimpour, J Hanaee… - Journal of Solution …, 2024 - Springer
The equilibrium molar solubility of 2-hydroxybenzoic acid (salicylic acid, SA) in pseudo-
binary mixed solvents of choline chloride/propylene glycol deep eutectic solvent (ChCl/PG …