Computational approaches for analyzing the mechanics of atherosclerotic plaques: a review

GA Holzapfel, JJ Mulvihill, EM Cunnane… - Journal of …, 2014 - Elsevier
Vulnerable and stable atherosclerotic plaques are heterogeneous living materials with
peculiar mechanical behaviors depending on geometry, composition, loading and boundary …

Carotid artery stenting simulation: from patient-specific images to finite element analysis

F Auricchio, M Conti, M De Beule, G De Santis… - Medical engineering & …, 2011 - Elsevier
The outcome of carotid artery stenting (CAS) depends on a proper selection of patients and
devices, requiring dedicated tools able to relate the device features with the target vessel. In …

A structural approach including the behavior of collagen cross-links to model patient-specific human carotid arteries

P Sáez, E Peña, MA Martínez - Annals of biomedical engineering, 2014 - Springer
In this work the mechanical response of the carotid arterial wall is studied. Some limitations
of previous models of the arterial wall are overcomed and variability of the fitting problem is …

Time-resolved simulation of blood flow through left anterior descending coronary artery: effect of varying extent of stenosis on hemodynamics

Y Zhao, H Wang, W Chen, W Sun, X Yu, C Sun… - BMC Cardiovascular …, 2023 - Springer
Background and objectives Real-time blood flow variation is crucial for understanding the
dynamic development of coronary atherosclerosis. The main objective of this study is to …

3D computational parametric analysis of eccentric atheroma plaque: influence of axial and circumferential residual stresses

M Cilla, E Peña, MA Martínez - Biomechanics and modeling in …, 2012 - Springer
Plaque rupture plays a role in the majority of acute coronary syndromes. Rupture has
usually been associated with stress concentrations, which are mainly affected by the plaque …

Our capricious vessels: the influence of stent design and vessel geometry on the mechanics of intracranial aneurysm stent deployment

S De Bock, F Iannaccone, G De Santis… - Journal of …, 2012 - Elsevier
There is a growing interest in virtual tools to assist clinicians in evaluating different
procedures and devices for endovascular treatment. In the present study we use finite …

Personalizing flow‐diverter intervention for cerebral aneurysms: from computational hemodynamics to biochemical modeling

TW Peach, M Ngoepe, K Spranger… - … journal for numerical …, 2014 - Wiley Online Library
This paper presents the computational modeling of a variety of flow‐diverting stents,
deployed in a number of patient‐specific aneurysm geometries. We consider virtual device …

Numerical simulations of patient-specific models with multiple plaques in human peripheral artery: a fluid-structure interaction analysis

D Wang, F Serracino-Inglott, J Feng - Biomechanics and Modeling in …, 2021 - Springer
Atherosclerotic plaque in the femoral is the leading cause of peripheral artery disease
(PAD), the worse consequence of which may lead to ulceration and gangrene of the feet …

3D patient-specific modeling and structural finite element analysis of atherosclerotic carotid artery based on computed tomography angiography

N Curcio, A Rosato, D Mazzaccaro, G Nano, M Conti… - Scientific reports, 2023 - nature.com
The assessment of carotid plaque vulnerability is a relevant clinical information that can help
prevent adverse cerebrovascular events. To this aim, in this study, we propose a patient …

An investigation into the role of different constituents in damage accumulation in arterial tissue and constitutive model development

M Ghasemi, DR Nolan, C Lally - Biomechanics and modeling in …, 2018 - Springer
Carotid atherosclerotic plaque rupture is one of the leading causes of stroke. Treatments for
atherosclerosis can induce tissue damage during the deployment of an intravascular device …