[HTML][HTML] Cerebral dysfunctions caused by sepsis during ageing

T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …

Prognostic accuracy of the quick sequential organ failure assessment for mortality in patients with suspected infection: a systematic review and meta-analysis

SM Fernando, A Tran, M Taljaard, W Cheng… - Annals of internal …, 2018 - acpjournals.org
Background: The quick Sequential Organ Failure Assessment (qSOFA) has been proposed
for prediction of mortality in patients with suspected infection. Purpose: To summarize and …

Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults

C Langelier, KL Kalantar, F Moazed… - Proceedings of the …, 2018 - National Acad Sciences
Lower respiratory tract infections (LRTIs) lead to more deaths each year than any other
infectious disease category. Despite this, etiologic LRTI pathogens are infrequently …

[HTML][HTML] Burden of community-acquired pneumonia and unmet clinical needs

J Ferreira-Coimbra, C Sarda, J Rello - Advances in therapy, 2020 - Springer
Community-acquired pneumonia (CAP) is the leading cause of death among infectious
diseases and an important health problem, having considerable implications for healthcare …

Management of pneumonia in critically ill patients

C Cillóniz, A Torres, MS Niederman - bmj, 2021 - bmj.com
Severe pneumonia is associated with high mortality (short and long term), as well as
pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of …

Updates on community acquired pneumonia management in the ICU

GB Nair, MS Niederman - Pharmacology & therapeutics, 2021 - Elsevier
While the world is grappling with the consequences of a global pandemic related to SARS-
CoV-2 causing severe pneumonia, available evidence points to bacterial infection with …

[HTML][HTML] Performance of the quick Sequential (sepsis-related) Organ Failure Assessment score as a prognostic tool in infected patients outside the intensive care unit …

JU Song, CK Sin, HK Park, SR Shim, J Lee - Critical Care, 2018 - Springer
Background The usefulness of the quick Sequential (Sepsis-related) Organ Failure
Assessment (qSOFA) score in providing bedside criteria for early prediction of poor …

[HTML][HTML] Head-to-head comparison of qSOFA and SIRS criteria in predicting the mortality of infected patients in the emergency department: a meta-analysis

J Jiang, J Yang, J Mei, Y Jin, Y Lu - Scandinavian journal of trauma …, 2018 - Springer
Background Recently, the concept of sepsis was redefined by an international task force.
This international task force of experts recommended using the quick Sequential Organ …

[HTML][HTML] Challenges in severe community-acquired pneumonia: a point-of-view review

A Torres, JD Chalmers, CS Dela Cruz… - Intensive care …, 2019 - Springer
Purpose Severe community-acquired pneumonia (SCAP) is still associated with substantial
morbidity and mortality. In this point-of-view review paper, a group of experts discuss the …

[HTML][HTML] Accuracy of quick Sequential Organ Failure Assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for predicting mortality …

S Maitra, A Som, S Bhattacharjee - Clinical Microbiology and Infection, 2018 - Elsevier
Objective To identify sensitivity, specificity and predictive accuracy of quick sequential organ
failure assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) …