Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Considerable progress has been made in elucidating the relationships between early life
psychobiological and environmental risk factors and the development of tobacco addiction …

Observational studies have suggested that smoking may increase the risk of cutaneous
squamous cell carcinoma (cSCC) while decreasing the risks of basal cell carcinoma (BCC) …

Introduction: Previous studies in adolescents were not adequately powered to accurately
disentangle genetic and environmental influences on smoking initiation (SI) across …

Backgrounds Although studies have demonstrated that the NCAM1–TTC12–ANKK1–DRD2
gene cluster plays essential roles in addictions in subjects of European and African origin …

Background Chronic obstructive pulmonary disease (COPD) is a multifactorial disorder
which is affected by external and internal risk factors. People with no external risk factors …

A new generation of community-and population-based research is combining measures of
social context, experience, and behavior with direct measures of physiology, gene sequence …

Background Smoking and use of Swedish smokeless tobacco (snus) are associated with
increased risk of type 2 diabetes (T2D). Our aim was to estimate the unique and shared …

Introduction Regulations of the sale of tobacco products to minors have been effective at
reducing adolescent tobacco use overall. However, these efforts may not be uniformly …

Variants in serotonergic genes are implicated in nicotine dependence (ND) in subjects of
European and African origin, but their involvement with smoking in Asians is largely …