Genes encoding SWI/SNF chromatin remodeling complex subunits are collectively mutated
in approximately 20% of human cancers. ARID1A is a SWI/SNF subunit gene whose protein …

Clear cell carcinoma of the ovary is a rare and distinct histotype of epithelial ovarian
carcinomas. Women diagnosed with clear cell carcinomas are usually younger and …

Patterns of genomic evolution between primary and metastatic breast cancer have not been
studied in large numbers, despite patients with metastatic breast cancer having dismal …

Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …

Although disordered chromatin organization has long been recognized as a feature of
cancer, the molecular underpinnings of chromatin structure, epigenetic regulation, and their …

Background: The risk and prognosis of ovarian cancer have not been well established in
women with endometriosis. Thus, we investigated the impact of endometriosis on the risk …

The SWI/SNF complexes, initially identified in yeast 20 years ago, are a family of multi-
subunit complexes that use the energy of adenosine triphosphate (ATP) hydrolysis to …

Ovarian carcinoma is the most lethal gynaecologic malignancy. Despite wide initial
sensibility to chemotherapy especially to platinum-based regimens, the vast majority of …

Endometriosis is a common gynecological disease affecting 6%–10% of women of
reproductive age and is characterized by the presence of endometrial-like tissue in …

The evasion of anti-growth signaling is an important characteristic of cancer cells. In order to
continue to proliferate, cancer cells must somehow uncouple themselves from the many …