Peripheral nerve injury treatments and advances: one health perspective

B Lopes, P Sousa, R Alvites, M Branquinho… - International journal of …, 2022 - mdpi.com
Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic
interventions, that can lead to the loss of structure and/or function impairment. These …

Adipose tissue-derived mesenchymal stem/stromal cells and their contribution to angiogenic processes in tissue regeneration

A Krawczenko, A Klimczak - International Journal of Molecular Sciences, 2022 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are widely described in the context of their
regenerative and immunomodulatory activity. MSCs are isolated from various tissues and …

[HTML][HTML] Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration

VK Sundaram, V Schütza, NH Schröter, A Backhaus… - Cell Metabolism, 2023 - cell.com
The peripheral nervous system harbors a remarkable potential to regenerate after acute
nerve trauma. Full functional recovery, however, is rare and critically depends on peripheral …

Intrathecal administration of conditioned serum from different species resolves Chemotherapy-Induced neuropathic pain in mice via secretory exosomes

T Buchheit, Y Huh, A Breglio, S Bang, J Xu… - Brain, behavior, and …, 2023 - Elsevier
Chemotherapy-induced peripheral neuropathy (CIPN) is the most prevalent neurological
complication of chemotherapy for cancer, and has limited effective treatment options …

Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics

SH Hiew, JK Wang, K Koh, H Yang, A Bacha, J Lin… - Acta Biomaterialia, 2021 - Elsevier
A short bioinspired octapeptide, GV8, can self-assemble under mild conditions into
biodegradable supramolecular physical hydrogels with high storage modulus and good …

Research progress of low-intensity pulsed ultrasound in the repair of peripheral nerve injury

X Liu, D Zou, Y Hu, Y He, J Lu - Tissue Engineering Part B: Reviews, 2023 - liebertpub.com
Peripheral nerve injury (PNI) is a common disease that has profound impact on the health of
patients, but has poor prognosis. The gold standard for the treatment of peripheral nerve …

[HTML][HTML] Natural polysaccharides and their derivatives as potential medical materials and drug delivery systems for the treatment of peripheral nerve injuries

SO Solomevich, CM Oranges, DF Kalbermatten… - Carbohydrate …, 2023 - Elsevier
Peripheral nerve repair following injury is one of the most serious problems in neurosurgery.
Clinical outcomes are often unsatisfactory and associated with a huge socioeconomic …

Potential role of growth factors controlled release in achieving enhanced neuronal trans-differentiation from mesenchymal stem cells for neural tissue repair and …

A Gupta, S Singh - Molecular Neurobiology, 2022 - Springer
With an increase in the incidence of neurodegenerative diseases, a need to replace
incapable conventional methods has arisen. To overcome this burden, stem cells therapy …

Therapeutical growth in oligodendroglial fate induction via transdifferentiation of stem cells for neuroregenerative therapy

S Dwivedi, P Choudhary, A Gupta, S Singh - Biochimie, 2023 - Elsevier
The merits of stem cell therapy and research are undisputed due to their widespread usage
in the treatment of neurodegenerative diseases and demyelinating disorders. Cell …

Intra-individual variability in the neuroprotective and promyelinating properties of conditioned culture medium obtained from human adipose mesenchymal stromal …

VA Baldassarro, F Perut, M Cescatti, V Pinto… - Stem Cell Research & …, 2023 - Springer
Background Greater knowledge of mesenchymal stromal cell (MSC)-based therapies is
driving the research into their secretome, identified as the main element responsible for their …